Lena Backlund
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Explore the profile of Lena Backlund including associated specialties, affiliations and a list of published articles.
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47
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3012
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Recent Articles
1.
OConnell K, Koromina M, van der Veen T, Boltz T, David F, Yang J, et al.
Nature
. 2025 Jan;
PMID: 39843750
Bipolar disorder is a leading contributor to the global burden of disease. Despite high heritability (60-80%), the majority of the underlying genetic determinants remain unknown. We analysed data from participants...
2.
Herrera-Rivero M, Adli M, Akiyama K, Akula N, Amare A, Ardau R, et al.
Int J Bipolar Disord
. 2024 Jun;
12(1):20.
PMID: 38865039
Background: Lithium (Li) remains the treatment of choice for bipolar disorders (BP). Its mood-stabilizing effects help reduce the long-term burden of mania, depression and suicide risk in patients with BP....
3.
Ou A, Rosenthal S, Adli M, Akiyama K, Akula N, Alda M, et al.
Transl Psychiatry
. 2024 Feb;
14(1):109.
PMID: 38395906
Lithium is the gold standard treatment for bipolar disorder (BD). However, its mechanism of action is incompletely understood, and prediction of treatment outcomes is limited. In our previous multi-omics study...
4.
Herrera-Rivero M, Adli M, Akiyama K, Akula N, Amare A, Ardau R, et al.
Res Sq
. 2023 Dec;
PMID: 38077040
Background: Lithium (Li) remains the treatment of choice for bipolar disorders (BP). Its mood-stabilizing effects help reduce the long-term burden of mania, depression and suicide risk in patients with BP....
5.
Kelsoe J, Ou A, Rosenthal S, Adli M, Akiyama K, Akula N, et al.
Res Sq
. 2023 Oct;
PMID: 37886563
Lithium is the gold standard treatment for bipolar disorder (BD). However, its mechanism of action is incompletely understood, and prediction of treatment outcomes is limited. In our previous multi-omics study...
6.
Herrera-Rivero M, Gutierrez-Fragoso K, Thalamuthu A, Amare A, Adli M, Akiyama K, et al.
Res Sq
. 2023 Jul;
PMID: 37461719
The link between bipolar disorder (BP) and immune dysfunction remains controversial. While epidemiological studies have long suggested an association, recent research has found only limited evidence of such a relationship....
7.
Amare A, Thalamuthu A, Schubert K, Fullerton J, Ahmed M, Hartmann S, et al.
Mol Psychiatry
. 2023 Jul;
28(12):5251-5261.
PMID: 37433967
Lithium is regarded as the first-line treatment for bipolar disorder (BD), a severe and disabling mental health disorder that affects about 1% of the population worldwide. Nevertheless, lithium is not...
8.
Amare A, Thalamuthu A, Schubert K, Fullerton J, Ahmed M, Hartmann S, et al.
Res Sq
. 2023 Feb;
PMID: 36824922
Lithium is regarded as the first-line treatment for bipolar disorder (BD), a severe and disabling mental disorder that affects about 1% of the population worldwide. Nevertheless, lithium is not consistently...
9.
Wikstrom F, Olsson C, Palm B, Roxhed N, Backlund L, Schalling M, et al.
J Pharm Biomed Anal
. 2023 Feb;
227:115269.
PMID: 36724686
Background: Lithium is a cornerstone in the treatment of bipolar disorder and is considered one of the most effective treatments in psychiatry at large. Lithium treatment requires individual dosing with...
10.
Ponzer K, Millischer V, Schalling M, Gissler M, Lavebratt C, Backlund L
Bipolar Disord
. 2023 Jan;
25(5):391-401.
PMID: 36651280
Objective: To determine if long-term lithium treatment is associated with protective effects or increased risk of vascular, neurological, and renal disorders. Methods: Using nationwide registers, we included all citizens of...