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Leia C Shuhaibar

Explore the profile of Leia C Shuhaibar including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 283
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Recent Articles
1.
Shuhaibar L, Kaci N, Egbert J, Horville T, Loisay L, Vigone G, et al.
JCI Insight . 2021 May; 6(9). PMID: 33986191
Activating mutations in fibroblast growth factor receptor 3 (FGFR3) and inactivating mutations in the natriuretic peptide receptor 2 (NPR2) guanylyl cyclase both result in decreased production of cyclic GMP in...
2.
Vigone G, Shuhaibar L, Egbert J, Uliasz T, Movsesian M, Jaffe L
Endocrinology . 2018 Apr; 159(5):2142-2152. PMID: 29608743
Luteinizing hormone (LH) acts on the granulosa cells that surround the oocyte in mammalian preovulatory follicles to cause meiotic resumption and ovulation. Both of these responses are mediated primarily by...
3.
Shuhaibar L, Robinson J, Vigone G, Shuhaibar N, Egbert J, Baena V, et al.
Elife . 2017 Dec; 6. PMID: 29199951
Activating mutations in fibroblast growth factor (FGF) receptor 3 and inactivating mutations in the NPR2 guanylyl cyclase both cause severe short stature, but how these two signaling systems interact to...
4.
Egbert J, Uliasz T, Shuhaibar L, Geerts A, Wunder F, Kleiman R, et al.
Biol Reprod . 2016 Mar; 94(5):110. PMID: 27009040
The meiotic cell cycle of mammalian oocytes in preovulatory follicles is held in prophase arrest by diffusion of cGMP from the surrounding granulosa cells into the oocyte. Luteinizing hormone (LH)...
5.
Shuhaibar L, Egbert J, Edmund A, Uliasz T, Dickey D, Yee S, et al.
Dev Biol . 2015 Nov; 409(1):194-201. PMID: 26522847
The meiotic cell cycle of mammalian oocytes starts during embryogenesis and then pauses until luteinizing hormone (LH) acts on the granulosa cells of the follicle surrounding the oocyte to restart...
6.
Shuhaibar L, Egbert J, Norris R, Lampe P, Nikolaev V, Thunemann M, et al.
Proc Natl Acad Sci U S A . 2015 Mar; 112(17):5527-32. PMID: 25775542
Meiosis in mammalian oocytes is paused until luteinizing hormone (LH) activates receptors in the mural granulosa cells of the ovarian follicle. Prior work has established the central role of cyclic...
7.
Egbert J, Shuhaibar L, Edmund A, Van Helden D, Robinson J, Uliasz T, et al.
Development . 2014 Sep; 141(18):3594-604. PMID: 25183874
In mammals, the meiotic cell cycle of oocytes starts during embryogenesis and then pauses. Much later, in preparation for fertilization, oocytes within preovulatory follicles resume meiosis in response to luteinizing...
8.
Robinson J, Zhang M, Shuhaibar L, Norris R, Geerts A, Wunder F, et al.
Dev Biol . 2012 May; 366(2):308-16. PMID: 22546688
In preovulatory ovarian follicles of mice, meiotic prophase arrest in the oocyte is maintained by cyclic GMP from the surrounding granulosa cells that diffuses into the oocyte through gap junctions....