Leen Van Simaey
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Explore the profile of Leen Van Simaey including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
573
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Recent Articles
1.
Siwe H, Aerssens A, Flour M, Ternest S, Van Simaey L, Verstraeten D, et al.
Heliyon
. 2024 Sep;
10(17):e37281.
PMID: 39296042
Background: Despite the many guidelines for reprocessing of medical instruments, challenges persist such as microbial resistance to biocides, corrosive effects on materials, and time-consuming reprocessing procedures. Ultraviolet (UV) C light-emitting...
2.
Versmessen N, Van Simaey L, Negash A, Vandekerckhove M, Hulpiau P, Vaneechoutte M, et al.
PLoS One
. 2024 Jun;
19(6):e0305650.
PMID: 38885212
Accurate DNA quantification is key for downstream application including library preparations for whole genome sequencing (WGS) and the quantification of standards for quantitative PCR. Two commonly used technologies for nucleic...
3.
Landlinger C, Oberbauer V, Podpera Tisakova L, Schwebs T, Berdaguer R, Van Simaey L, et al.
Antimicrob Agents Chemother
. 2022 Apr;
66(5):e0231921.
PMID: 35416708
Antibiotics are the mainstay of therapy for bacterial vaginosis (BV). However, the rate of treatment failure in patients with recurrent BV is about 50%. Herein, we investigated potential mechanisms of...
4.
Latka A, Van Simaey L, Reynders M, Cools P, Rogier T, Lebbe B, et al.
Antibiotics (Basel)
. 2022 Jan;
11(1).
PMID: 35052988
Quantification of the number of living cells in biofilm or after eradication treatments of biofilm, is problematic for different reasons. We assessed the performance of pre-treatment of DNA, planktonic cells...
5.
Lebeaux D, Merabishvili M, Caudron E, Lannoy D, Van Simaey L, Duyvejonck H, et al.
Viruses
. 2021 Jan;
13(1).
PMID: 33466377
Bacteriophages are a promising therapeutic strategy among cystic fibrosis and lung-transplanted patients, considering the high frequency of colonization/infection caused by pandrug-resistant bacteria. However, little clinical data are available regarding the...
6.
Landlinger C, Tisakova L, Oberbauer V, Schwebs T, Muhammad A, Latka A, et al.
Pathogens
. 2021 Jan;
10(1).
PMID: 33435575
Bacterial vaginosis is characterized by an imbalance of the vaginal microbiome and a characteristic biofilm formed on the vaginal epithelium, which is initiated and dominated by bacteria, and is frequently...
7.
Rodriguez A, Duyvejonck H, van Belleghem J, Gryp T, Van Simaey L, Vermeulen S, et al.
PLoS One
. 2020 Feb;
15(2):e0229423.
PMID: 32084228
RNA quality and quantity are important factors for ensuring the accuracy of gene expression analysis and other RNA-based downstream applications. Thus far, only a limited number of methodological studies have...
8.
Duyvejonck H, Merabishvili M, Pirnay J, De Vos D, Verbeken G, Van Belleghem J, et al.
Sci Rep
. 2019 Sep;
9(1):13893.
PMID: 31554892
To determine phage titers accurately, reproducibly and in a non-laborious and cost-effective manner, we describe the development of a qPCR platform for molecular quantification of five phages present in bacteriophage...
9.
Vaneechoutte M, Guschin A, Van Simaey L, Gansemans Y, Van Nieuwerburgh F, Cools P
Int J Syst Evol Microbiol
. 2019 Jan;
69(3):679-687.
PMID: 30648938
Whole genome sequence analysis (digital DNA-DNA hybridization and average nucleotide identity) was carried out for 81 sequenced full genomes of the genus Gardnerella, including ten determined in this study, and...
10.
Jonckheere L, Schelstraete P, Van Simaey L, Van Braeckel E, Willekens J, Van Daele S, et al.
J Cyst Fibros
. 2018 Apr;
17(6):729-735.
PMID: 29655935
Methods: Over a 14-year period, sputa were cultured from 80 CF-patients (age range: 2-51 years), from a first ever isolation of P. aeruginosa onwards. Patients with a positive culture for...