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Lee D Oliver Jr

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Articles 13
Citations 162
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Recent Articles
1.
OBier N, Patel D, Oliver Jr L, Miller D, Marconi R
Mol Oral Microbiol . 2020 Nov; 36(1):50-57. PMID: 33219611
Treponema denticola is a proteolytic anaerobic spirochete and key contributor to periodontal disease of microbial etiology. As periodontal disease develops and progresses, T. denticola thrives in the hostile environment of...
2.
Izac J, Camire A, Schuler E, Hatke A, OBier N, Oliver Jr L, et al.
mSphere . 2020 Aug; 5(4). PMID: 32817454
Lyme disease and anaplasmosis are tick-borne bacterial diseases caused by and species, respectively. A comprehensive analysis of the exposure of eastern coyotes () in the northeastern United States to tick-borne...
3.
Green R, Naimi W, Oliver Jr L, OBier N, Cho J, Conrad D, et al.
mBio . 2020 Jan; 11(1). PMID: 31992623
Diverse intracellular pathogens rely on eukaryotic cell surface disulfide reductases to invade host cells. Pharmacologic inhibition of these enzymes is cytotoxic, making it impractical for treatment. Identifying and mechanistically dissecting...
4.
Izac J, OBier N, Oliver Jr L, Camire A, Earnhart C, LeBlanc Rhodes D, et al.
Vaccine . 2020 Jan; 38(8):1915-1924. PMID: 31959423
Experimental Outer surface protein (Osp) C based subunit chimeritope vaccinogens for Lyme disease (LD) were assessed for immunogenicity, structure, ability to elicit antibody (Ab) responses to divergent OspC proteins, and...
5.
Kostick-Dunn J, Izac J, Freedman J, Szkotnicki L, Oliver Jr L, Marconi R
Front Cell Infect Microbiol . 2018 Jul; 8:213. PMID: 30050868
Cyclic-di-GMP (c-di-GMP) contributes to the regulation of processes required by the Lyme disease (LD) spirochetes to complete the tick-mammal enzootic cycle. Our understanding of the effector mechanisms of c-di-GMP in...
6.
Sarkar J, Miller D, Oliver Jr L, Marconi R
J Bacteriol . 2018 Jul; 200(18). PMID: 29986942
Periodontal disease (PD) results from a shift in the composition of the microbial community of the subgingival crevice. As the bacterial population transitions from Gram-positive bacteria to predominantly Gram-negative anaerobes...
7.
Reed L, OBier N, Oliver Jr L, Hoffman P, Marconi R
J Periodontol . 2018 Jun; 89(12):1467-1474. PMID: 29958324
Background: Periodontal disease is a polymicrobial infection characterized by inflammation of the gingiva, alveolar bone resorption and tooth loss. As periodontal disease progresses, oral treponemes (spirochetes) become dominant bacteria in...
8.
Izac J, Oliver Jr L, Earnhart C, Marconi R
Vaccine . 2017 May; 35(24):3178-3185. PMID: 28479174
The lipoprotein OspA is produced by the Lyme disease spirochetes primarily in unfed ticks. OspA production is down-regulated by the blood meal and it is not produced in mammals except...
9.
Beyer A, Rodino K, VieBrock L, Green R, Tegels B, Oliver Jr L, et al.
Cell Microbiol . 2017 Jan; 19(7). PMID: 28103630
Orientia tsutsugamushi causes scrub typhus, a potentially fatal infection that afflicts 1 million people annually. This obligate intracellular bacterium boasts one of the largest microbial arsenals of ankyrin repeat-containing protein...
10.
Hebert K, Seidman D, Oki A, Izac J, Emani S, Oliver Jr L, et al.
Infect Immun . 2016 Dec; 85(3). PMID: 27993973
causes bovine anaplasmosis, a debilitating and potentially fatal tick-borne infection of cattle. Because is an obligate intracellular organism, its adhesins that mediate entry into host cells are essential for survival....