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Lee Ann Cohen

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Articles 6
Citations 356
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Recent Articles
1.
Caviston J, Cohen L, Donaldson J
Cytoskeleton (Hoboken) . 2014 Jun; 71(6):380-94. PMID: 24916416
Arf proteins regulate membrane traffic and organelle structure. Although Arf6 is known to initiate actin-based changes in cell surface architecture, Arf1 may also function at the plasma membrane. Here we...
2.
Cohen L, Donaldson J
Curr Protoc Cell Biol . 2010 Sep; Chapter 3:Unit 14.12.1-17. PMID: 20853342
This unit describes techniques and approaches that can be used to study the functions of the ADP-ribosylation factor (Arf) GTP-binding proteins in cells. There are six mammalian Arfs and many...
3.
Donaldson J, Porat-Shliom N, Cohen L
Cell Signal . 2008 Jul; 21(1):1-6. PMID: 18647649
There is increasing interest in endocytosis that occurs independently of clathrin coats and the fates of membrane proteins internalized by this mechanism. The appearance of clathrin-independent endocytic and membrane recycling...
4.
Cohen L, Honda A, Varnai P, Brown F, Balla T, Donaldson J
Mol Biol Cell . 2007 Apr; 18(6):2244-53. PMID: 17409355
ARNO is a soluble guanine nucleotide exchange factor (GEF) for the Arf family of GTPases. Although in biochemical assays ARNO prefers Arf1 over Arf6 as a substrate, its localization in...
5.
Cohen L, Guan J
Curr Cancer Drug Targets . 2005 Dec; 5(8):629-43. PMID: 16375667
Focal adhesion kinase (FAK) is a tyrosine kinase whose phosphorylation state and activity is tightly linked to cell adhesion to the extracellular matrix through integrin receptors. FAK's regulation by adhesion...
6.
Cohen L, Guan J
J Biol Chem . 2004 Dec; 280(9):8197-207. PMID: 15611137
We have previously described regulation of focal adhesion kinase (FAK) by its amino-terminal FERM-like domain through an autoinhibitory interaction with its kinase domain (Cooper, L. A., Shen, T. L., and...