Leandro Cerchietti
Overview
Explore the profile of Leandro Cerchietti including associated specialties, affiliations and a list of published articles.
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Articles
89
Citations
4158
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Recent Articles
11.
Cayrol F, Revuelta M, Debernardi M, Paulazo A, Phillip J, Zamponi N, et al.
Mol Cancer Ther
. 2022 Jul;
21(9):1485-1496.
PMID: 35793463
Teaser: Inhibiting αVβ3 integrin improves the antineoplastic effect of bexarotene while maintaining lymphoma immunity.
12.
Gomari D, Schweickart A, Cerchietti L, Paietta E, Fernandez H, Al-Amin H, et al.
Commun Biol
. 2022 Jun;
5(1):645.
PMID: 35773471
Dimensionality reduction approaches are commonly used for the deconvolution of high-dimensional metabolomics datasets into underlying core metabolic processes. However, current state-of-the-art methods are widely incapable of detecting nonlinearities in metabolomics...
13.
Xia M, David L, Teater M, Gutierrez J, Wang X, Meydan C, et al.
Cancer Discov
. 2022 Jun;
12(8):1922-1941.
PMID: 35658124
Significance: ABC-DLBCLs feature frequent mutations of signaling mediators that converge on the CBM complex. We use structure-function approaches to reveal that BCL10 mutations fall into two distinct biochemical classes. Both...
14.
Clauzure M, Taquez Delgado M, Phillip J, Revuelta M, Cerchietti L, Medina V
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163302
The discovery of the human histamine H4 receptor (H4R) has contributed to our understanding of the role of histamine in numerous physiological and pathological conditions, including tumor development and progression....
15.
Li M, Teater M, Hong J, Park N, Duy C, Shen H, et al.
Blood Cancer Discov
. 2022 Jan;
3(1):50-65.
PMID: 35019856
Diffuse large B-cell lymphomas (DLBCL) are broadly dependent on anaplerotic metabolism regulated by mitochondrial SIRT3. Herein we find that translational upregulation of ATF4 is coupled with anaplerotic metabolism in DLBCLs...
16.
Marullo R, Castro M, Yomtoubian S, Calvo-Vidal M, Revuelta M, Krumsiek J, et al.
Sci Adv
. 2021 Nov;
7(45):eabg1964.
PMID: 34739311
Selected patients with brain metastases (BM) are candidates for radiotherapy. A lactatogenic metabolism, common in BM, has been associated with radioresistance. We demonstrated that BM express nitric oxide (NO) synthase...
17.
Brem E, Li H, Beaven A, Caimi P, Cerchietti L, Alizadeh A, et al.
J Geriatr Oncol
. 2021 Oct;
13(2):258-264.
PMID: 34686472
Diffuse large B cell lymphoma (DLBCL) is an aggressive but potentially curable malignancy; however, cure is highly dependent on the ability to deliver intensive, anthracycline-based chemoimmunotherapy. Nearly one third of...
18.
Calvo-Vidal M, Zamponi N, Krumsiek J, Stockslager M, Revuelta M, Phillip J, et al.
Cancer Res
. 2021 Sep;
81(20):5202-5216.
PMID: 34479963
HSP90 is critical for maintenance of the cellular proteostasis. In cancer cells, HSP90 also becomes a nucleating site for the stabilization of multiprotein complexes including signaling pathways and transcription complexes....
19.
Martin P, Bartlett N, Chavez J, Reagan J, Smith S, LaCasce A, et al.
Blood
. 2021 Aug;
139(8):1147-1159.
PMID: 34428285
Resistance to standard immunochemotherapy remains an unmet challenge in diffuse large B-cell lymphoma (DLBCL), and aberrant DNA methylation may contribute to chemoresistance. Promising early-phase results were reported with rituximab, cyclophosphamide,...
20.
Napoli S, Cascione L, Rinaldi A, Spriano F, Guidetti F, Zhang F, et al.
Haematologica
. 2021 Jun;
107(5):1131-1143.
PMID: 34162177
Enhancers are regulatory regions of DNA, which play a key role in cell-type specific differentiation and development. Most active enhancers are transcribed into enhancer RNA (eRNA) that can regulate transcription...