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Leah K OShea

Explore the profile of Leah K OShea including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 107
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Recent Articles
1.
Abdulkhalek S, Geen O, Brodhagen L, Haxho F, Alghamdi F, Allison S, et al.
Clin Transl Med . 2016 Mar; 3(1):28. PMID: 26932374
Background: Snail, a transcriptional factor and repressor of E-cadherin is well known for its role in cellular invasion. It can regulate epithelial to mesenchymal transition (EMT) during embryonic development and...
2.
OShea L, Abdulkhalek S, Allison S, Neufeld R, Szewczuk M
Onco Targets Ther . 2014 Jan; 7:117-34. PMID: 24470763
Background: Resistance to drug therapy, along with high rates of metastasis, contributes to the low survival rate in patients diagnosed with pancreatic cancer. An alternate treatment for human pancreatic cancer...
3.
Gilmour A, Abdulkhalek S, Cheng T, Alghamdi F, Jayanth P, OShea L, et al.
Cell Signal . 2013 Sep; 25(12):2587-603. PMID: 23993964
Epidermal growth factor (EGF)-induced EGFR tyrosine kinase receptor activation in cancer cell survival responses has become a strategic molecular-targeting clinical therapeutic intent, but the failures of these targeted approaches in...