Lea Hampe
Overview
Explore the profile of Lea Hampe including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
124
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0
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Recent Articles
1.
Thibaudin M, Roussot N, Burlot C, Schmitt A, Vincent J, Tharin Z, et al.
Signal Transduct Target Ther
. 2025 Jan;
10(1):22.
PMID: 39820336
In the tumour microenvironment, IL-1α promotes neoangiogenesis, matrix remodelling, tumour proliferation, chemoresistance, and metastases. Highly expressed in human colorectal cancers, IL-1α is associated with poor prognosis. XB2001, a fully human...
2.
Roussot N, Thibaudin M, Fumet J, Daumoine S, Hampe L, Rebe C, et al.
Front Immunol
. 2024 Aug;
15:1437961.
PMID: 39170614
A patient with a PD-L1-negative, TMB-low, co-mutated metastatic non-small cell lung cancer (NSCLC) experienced a multisite radiological progression at 3 months after initiation of chemoimmunotherapy as first-line treatment for metastatic...
3.
Hampe L, Daumoine S, Limagne E, Roussot N, Borsotti F, Vincent J, et al.
Cancer Immunol Immunother
. 2024 May;
73(7):133.
PMID: 38753169
Background: Glioblastoma (GBM) is a primary brain tumor with a dismal prognosis, often resistant to immunotherapy and associated with immune suppression. This study aimed to assess the impact of steroids...
4.
Daumoine S, Hampe L, Limagne E, Ghiringhelli F, Thibaudin M
STAR Protoc
. 2023 Nov;
4(4):102658.
PMID: 37910510
Here, we present a protocol for the simultaneous analysis of peripheral and intratumoral lymphocyte function by flow cytometry. Using tumor and blood samples from patients with colorectal cancer, we describe...
5.
Thibaudin M, Fumet J, Chibaudel B, Bennouna J, Borg C, Martin-Babau J, et al.
Nat Med
. 2023 Aug;
29(8):2087-2098.
PMID: 37563240
Although patients with microsatellite instable metastatic colorectal cancer (CRC) benefit from immune checkpoint blockade, chemotherapy with targeted therapies remains the only therapeutic option for microsatellite stable (MSS) tumors. The single-arm,...
6.
Thibaudin M, Limagne E, Hampe L, Ballot E, Truntzer C, Ghiringhelli F
Cancer Immunol Immunother
. 2022 Mar;
71(10):2549-2563.
PMID: 35292828
Microsatellite stable colorectal cancers (MSS-CRC) are resistant to anti-PD-1/PD-L1 therapy but the combination of immune checkpoints inhibitors (ICI) could be a clue to reverse resistance. Our aim was to evaluate...
7.
Niogret J, Berger H, Rebe C, Mary R, Ballot E, Truntzer C, et al.
J Immunother Cancer
. 2021 Jun;
9(6).
PMID: 34103351
Background: T follicular helper cells (Tfh) are essential to shape B cell response during germinal center formation. Tfh accumulation has been reported in various human cancers, with positive or negative...
8.
Thibaudin M, Fumet J, Bon M, Hampe L, Limagne E, Ghiringhelli F
Eur J Cancer
. 2020 Sep;
139:70-80.
PMID: 32977223
Background: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, has caused a major pandemic. Patients with cancer are at higher risk of severe COVID-19. We aimed...