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Le Luong

Explore the profile of Le Luong including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 271
Followers 0
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Recent Articles
1.
Law J, Kwek I, Svystun O, Lim J, Tan C, Luong L, et al.
Biochim Biophys Acta Mol Cell Res . 2018 Feb; 1865(5):684-694. PMID: 29470995
MOAP-1 is a pro-apoptotic tumor suppressor molecule with a growing set of known interacting partners. We have demonstrated that during death receptor-dependent apoptosis, MOAP-1 is recruited to TNF-R1 or TRAIL-R1,...
2.
Luong L, Duckles H, Schenkel T, Mahmoud M, Tremoleda J, Wylezinska-Arridge M, et al.
Thromb Haemost . 2016 Apr; 116(1):181-90. PMID: 27075869
Blood flow generates wall shear stress (WSS) which alters endothelial cell (EC) function. Low WSS promotes vascular inflammation and atherosclerosis whereas high uniform WSS is protective. Ivabradine decreases heart rate...
3.
Law J, Salla M, Zare A, Wong Y, Luong L, Volodko N, et al.
J Biol Chem . 2015 Aug; 290(40):24100-18. PMID: 26269600
Modulator of apoptosis 1 (MOAP-1) is a BH3-like protein that plays key roles in cell death or apoptosis. It is an integral partner to the tumor suppressor protein, Ras association...
4.
Enesa K, Moll H, Luong L, Ferran C, Evans P
FASEB J . 2015 Feb; 29(5):1869-78. PMID: 25667218
A20 protects against pathologic vascular remodeling by inhibiting the inflammatory transcription factor NF-κB. A20's function has been attributed to ubiquitin editing of receptor-interacting protein 1 (RIP1) to influence activity/stability. The...
5.
Warboys C, De Luca A, Amini N, Luong L, Duckles H, Hsiao S, et al.
Arterioscler Thromb Vasc Biol . 2014 Mar; 34(5):985-95. PMID: 24651677
Objective: Although atherosclerosis is associated with systemic risk factors such as age, high cholesterol, and obesity, plaque formation occurs predominately at branches and bends that are exposed to disturbed patterns...
6.
Nguyen B, Luong L, Naase H, Vives M, Jakaj G, Finch J, et al.
J Thorac Cardiovasc Surg . 2014 Feb; 148(2):690-697.e3. PMID: 24521949
Objectives: Systemic inflammatory responses are a major cause of morbidity and mortality in patients undergoing cardiac surgery with cardiopulmonary bypass. However, the underlying molecular mechanisms for systemic inflammation in response...
7.
Agellon L, Drozdowski L, Li L, Iordache C, Luong L, Clandinin M, et al.
Biochim Biophys Acta . 2007 Oct; 1771(10):1283-8. PMID: 17905650
Mice lacking I-FABP (encoded by the Fabp2 gene) exhibit a gender dimorphic response to a high fat/cholesterol diet challenge characterized by hepatomegaly in male I-FABP-deficient mice. In this study, we...
8.
Partridge J, Carlsen H, Enesa K, Chaudhury H, Zakkar M, Luong L, et al.
FASEB J . 2007 Jun; 21(13):3553-61. PMID: 17557931
Regions of the arterial tree exposed to laminar flow, which exerts high shear stress, are protected from inflammation, endothelial cell (EC) death and atherosclerosis. TNFalpha activates NF-kappaB transcription factors, which...
9.
Agellon L, Li L, Luong L, Uwiera R
Mol Cell Biochem . 2006 Mar; 284(1-2):159-66. PMID: 16532262
It was shown previously that the intestinal fatty acid binding protein (I-FABP) is not essential for the absorption of dietary fat. One notable feature of I-FABP deficiency was the enhancement...
10.
Maeda T, Espino R, Chomey E, Luong L, Bano A, Meakins D, et al.
Carcinogenesis . 2005 May; 26(10):1804-10. PMID: 15917306
Ultraviolet light (UV)-induced DNA damage is repaired primarily by the nucleotide excision repair (NER) pathway. Gadd45 is a multifunctional protein that regulates NER. Gadd45-deficient keratinocytes fail to repair UV-induced DNA...