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Lazaro Gil Gonzalez

Explore the profile of Lazaro Gil Gonzalez including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 17
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Recent Articles
1.
Won K, Gil Gonzalez L, Cruz-Leal Y, Pavon Oro A, Lazarus A
J Immunol . 2024 Mar; 212(10):1531-1539. PMID: 38506555
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by low platelet counts primarily due to antiplatelet autoantibodies. Anti-D is a donor-derived polyclonal Ab against the rhesus D Ag on erythrocytes...
2.
Nikkhoi S, Yang G, Owji H, Grizotte-Lake M, Cohen R, Gil Gonzalez L, et al.
J Immunother Cancer . 2024 Mar; 12(3). PMID: 38490714
Background: In a prior report, we detailed the isolation and engineering of a bispecific killer cell engager, referred to as BiKE:E5C1. The BiKE:E5C1 exhibits high affinity/specificity for the CD16a activating...
3.
Gil Gonzalez L, Won K, Tawhidi Z, Cummins E, Cruz-Leal Y, Tundidor Cabado Y, et al.
Blood Adv . 2024 Feb; 8(8):1869-1879. PMID: 38330193
Fc gamma receptor (FcγR) IIIA is an important receptor for immunoglobulin G (IgG) and is involved in immune defense mechanisms as well as tissue destruction in some autoimmune diseases including...
4.
Cruz-Leal Y, Norris P, Gil Gonzalez L, Marjoram D, Wabnitz H, Shan Y, et al.
Blood . 2023 Nov; 143(9):807-821. PMID: 37946269
Red blood cell (RBC) alloimmunization to paternal antigens during pregnancy can cause hemolytic disease of the fetus and newborn (HDFN). This severe and potentially fatal neonatal disorder can be prevented...
5.
Norris P, Tawhidi Z, Sachs U, Cserti-Gazdewich C, Lin Y, Callum J, et al.
Blood Adv . 2023 Apr; 7(14):3561-3572. PMID: 37042934
Humoral antiplatelet factors, such as autoantibodies, are thought to primarily clear platelets by triggering macrophage phagocytosis in immune thrombocytopenia (ITP). However, there are few studies characterizing the capacity and mechanisms...
6.
Gil Gonzalez L, Fernandez-Marrero Y, Norris P, Tawhidi Z, Shan Y, Cruz-Leal Y, et al.
PLoS One . 2022 Dec; 17(12):e0278365. PMID: 36516219
Fc gamma receptors (FcγRs) are critical effector receptors for immunoglobulin G (IgG) antibodies. On macrophages, FcγRs mediate multiple effector functions, including phagocytosis, but the individual contribution of specific FcγRs to...
7.
Martinez R, Nunez de Villavicencio-Diaz T, Sanchez A, Ramos Y, Ferro J, Gil Gonzalez L, et al.
Biochem Biophys Rep . 2017 Sep; 5:379-387. PMID: 28955845
Background: Growth hormone secretagogues (GHS), among other factors, regulate the release of GH. The biological activity of the secretagogue peptide A233 as a promoter of growth and innate immunity in...
8.
Lazo Vazquez L, Suzarte Portal E, Castro Velazco J, Yen P, Dung L, Gil Gonzalez L, et al.
Clin Transl Immunology . 2017 Apr; 6(3):e135. PMID: 28435678
One of the major problems faced for the development of a vaccine against Dengue virus is the lack of a suitable animal model. Although non-human primates do not show overt...
9.
Lazo Vazquez L, Gil Gonzalez L, Marcos Lopez E, Perez Fuentes Y, Cervetto de Armas L, Brown Richards E, et al.
Viral Immunol . 2017 Apr; 30(5):350-358. PMID: 28418786
Our group has developed a subunit vaccine candidate against Dengue virus (DENV) based on two different viral regions, the domain III of the envelope protein and the capsid protein. The...