Lawrence M Chen
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Explore the profile of Lawrence M Chen including associated specialties, affiliations and a list of published articles.
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13
Citations
153
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Recent Articles
1.
Chen L, Quinn L, York J, Polaske T, Nelson A, Appadoo V, et al.
ACS Omega
. 2025 Mar;
10(7):7295-7305.
PMID: 40028086
The ability to prevent bacterial adhesion on surfaces and to facilitate the removal of bacteria once they have already contaminated or colonized a surface is important in a broad range...
2.
Henry M, Chen L, Ducharme L, Devault-Tousignant C, Rosberger Z, Frenkiel S, et al.
JAMA Otolaryngol Head Neck Surg
. 2024 May;
150(7):598-606.
PMID: 38814668
Importance: Although patients with head and neck cancer (HNC) have been shown to experience high distress, few longitudinal studies include a comprehensive evaluation of biopsychosocial factors affecting quality of life...
3.
Chen L, Pokhvisneva I, Lahti-Pulkkinen M, Kvist T, Baldwin J, Parent C, et al.
J Am Acad Child Adolesc Psychiatry
. 2023 Nov;
63(6):640-651.
PMID: 37977417
Objective: Prenatal maternal symptoms of depression and anxiety are associated with an increased risk for child socioemotional and behavioral difficulties, supporting the fetal origins of mental health hypothesis. However, to...
4.
Henry M, Harvey R, Chen L, Meaney M, Nguyen T, Kao H, et al.
J Affect Disord
. 2023 Mar;
331:149-157.
PMID: 36948466
Objective: The primary purpose of this study was to investigate the contribution of genetic predispositions to depression and inflammation, as measured through polygenic risk scores, on symptom burden (physical and...
5.
Batra A, Chen L, Wang Z, Parent C, Pokhvisneva I, Patel S, et al.
Front Neurosci
. 2021 Sep;
15:704785.
PMID: 34539334
While the co-morbidity between metabolic and psychiatric behaviors is well-established, the mechanisms are poorly understood, and exposure to early life adversity (ELA) is a common developmental risk factor. ELA is...
6.
Gahan C, Patel S, Chen L, Manson D, Ehmer Z, Blackwell H, et al.
Langmuir
. 2021 Jul;
37(30):9120-9136.
PMID: 34283628
We report that -acyl-l-homoserine lactones (AHLs), a class of nonionic amphiphiles that common bacteria use as signals to coordinate group behaviors, can promote large-scale remodeling in model lipid membranes. Characterization...
7.
Chen L, Tollenaar M, Hari Dass S, Bouvette-Turcot A, Pokhvisneva I, Gaudreau H, et al.
Dev Psychopathol
. 2021 Jan;
32(5):1810-1821.
PMID: 33427178
Maternal antenatal depression strongly influences child mental health but with considerable inter-individual variation that is, in part, linked to genotype. The challenge is to effectively capture the genotypic influence. We...
8.
Maurer D, Ghloum J, Gibson L, Watson M, Chen L, Akins K, et al.
Proc Natl Acad Sci U S A
. 2020 Apr;
117(18):10089-10096.
PMID: 32321833
Synesthesia is a neurologic trait in which specific inducers, such as sounds, automatically elicit additional idiosyncratic percepts, such as color (thus "colored hearing"). One explanation for this trait-and the one...
9.
Hari Dass S, McCracken K, Pokhvisneva I, Chen L, Garg E, Nguyen T, et al.
EBioMedicine
. 2019 Mar;
42:188-202.
PMID: 30922963
Background: Activation of brain insulin receptors modulates reward sensitivity, inhibitory control and memory. Variations in the functioning of this mechanism likely associate with individual differences in the risk for related...
10.
Chen L, Yao N, Garg E, Zhu Y, Nguyen T, Pokhvisneva I, et al.
BMC Bioinformatics
. 2018 Aug;
19(1):295.
PMID: 30089455
Background: Polygenic risk scores (PRS) describe the genomic contribution to complex phenotypes and consistently account for a larger proportion of variance in outcome than single nucleotide polymorphisms (SNPs) alone. However,...