Lauri G Lintott
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Explore the profile of Lauri G Lintott including associated specialties, affiliations and a list of published articles.
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3
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9
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Recent Articles
1.
Gertsenstein M, Lintott L, Nutter L
Curr Protoc
. 2025 Feb;
5(2):e70109.
PMID: 39999224
Mice carrying patient-associated base changes are powerful tools to define the causality of single-nucleotide variants to disease states. Epitope tags enable immuno-based studies of genes for which no antibodies are...
2.
Elrick H, Peterson K, Willis B, Lanza D, Acar E, Ryder E, et al.
Sci Rep
. 2024 Sep;
14(1):22626.
PMID: 39349521
The International Mouse Phenotyping Consortium (IMPC) systematically produces and phenotypes mouse lines with presumptive null mutations to provide insight into gene function. The IMPC now uses the programmable RNA-guided nuclease...
3.
Peterson K, Khalouei S, Hanafi N, Wood J, Lanza D, Lintott L, et al.
Commun Biol
. 2023 Jun;
6(1):626.
PMID: 37301944
Genome editing with CRISPR-associated (Cas) proteins holds exceptional promise for "correcting" variants causing genetic disease. To realize this promise, off-target genomic changes cannot occur during the editing process. Here, we...
4.
Lintott L, Nutter L
Methods Mol Biol
. 2023 Mar;
2631:53-101.
PMID: 36995664
Genetically engineered mice are used as avatars to understand mammalian gene function and develop therapies for human disease. During genetic modification, unintended changes can occur, and these changes may result...