Laurent Gauthier
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Explore the profile of Laurent Gauthier including associated specialties, affiliations and a list of published articles.
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61
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3715
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Recent Articles
11.
Demaria O, Gauthier L, Debroas G, Vivier E
Eur J Immunol
. 2021 Jun;
51(8):1934-1942.
PMID: 34145579
Immuno-oncology is revolutionizing the treatment of cancers, by inducing the recognition and elimination of tumor cells by the immune system. Recent advances have focused on generating or unleashing tumor antigen-specific...
12.
Putative determinants of virulence in , the bacterial agent causing European foulbrood in honey bees
Grossar D, Kilchenmann V, Forsgren E, Charriere J, Gauthier L, Chapuisat M, et al.
Virulence
. 2020 May;
11(1):554-567.
PMID: 32456539
is a bacterial pathogen that causes epidemic outbreaks of European foulbrood (EFB) in honey bee populations. The pathogenicity of a bacterium depends on its virulence, and understanding the mechanisms influencing...
13.
Delauzun V, Amigues B, Gaubert A, Leone P, Grange M, Gauthier L, et al.
Methods
. 2020 Mar;
180:35-44.
PMID: 32156657
Producing intact recombinant membrane proteins for structural studies is an inherently challenging task due to their requirement for a cell-lipid environment. Most of the procedures developed involve isolating the protein...
14.
Gauthier L, Vivier E
Cell
. 2020 Mar;
180(5):822-824.
PMID: 32142673
Monoclonal antibodies (mAbs) targeting antigens expressed at the surface of tumor cells are widely used for cancer control in clinics, but these treatments need to be improved. Chew et al....
15.
Cornen S, Andre P, Gauthier L, Morel Y, Vivier E
Med Sci (Paris)
. 2020 Jan;
35(12):990-992.
PMID: 31903904
No abstract available.
16.
Gauthier L, Morel A, Anceriz N, Rossi B, Blanchard-Alvarez A, Grondin G, et al.
Cell
. 2019 Jun;
177(7):1701-1713.e16.
PMID: 31155232
Over the last decade, various new therapies have been developed to promote anti-tumor immunity. Despite interesting clinical results in hematological malignancies, the development of bispecific killer-cell-engager antibody formats directed against...
17.
Perrot I, Michaud H, Giraudon-Paoli M, Augier S, Docquier A, Gros L, et al.
Cell Rep
. 2019 May;
27(8):2411-2425.e9.
PMID: 31116985
Immune checkpoint inhibitors have revolutionized cancer treatment. However, many cancers are resistant to ICIs, and the targeting of additional inhibitory signals is crucial for limiting tumor evasion. The production of...
18.
Andre P, Denis C, Soulas C, Bourbon-Caillet C, Lopez J, Arnoux T, et al.
Cell
. 2018 Dec;
175(7):1731-1743.e13.
PMID: 30503213
Checkpoint inhibitors have revolutionized cancer treatment. However, only a minority of patients respond to these immunotherapies. Here, we report that blocking the inhibitory NKG2A receptor enhances tumor immunity by promoting...
19.
Djukic M, Erler S, Leimbach A, Grossar D, Charriere J, Gauthier L, et al.
Genes (Basel)
. 2018 Aug;
9(8).
PMID: 30127293
In Europe, approximately 84% of cultivated crop species depend on insect pollinators, mainly bees. (the Western honey bee) is the most important commercial pollinator worldwide. The Gram-positive bacterium is the...
20.
Cassagne M, Porterie M, Gauthier L, Chapotot E, Soler V, Malecaze F, et al.
J Cataract Refract Surg
. 2018 Apr;
44(3):266-273.
PMID: 29703283
Purpose: To evaluate the efficacy and safety of the combined implantation of a monofocal intraocular lens (IOL) in the capsular bag with a diffractive multifocal IOL designed for sulcus placement...