Laurent Gauthier
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Explore the profile of Laurent Gauthier including associated specialties, affiliations and a list of published articles.
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61
Citations
3715
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Recent Articles
1.
Demaria O, Habif G, Vetizou M, Gauthier L, Remark R, Chiossone L, et al.
Sci Immunol
. 2024 Nov;
9(101):eadp3720.
PMID: 39546590
NK cells offer a promising alternative to T cell therapies in cancer. We evaluated IPH6501, a clinical-stage, tetraspecific NK cell engager (NKCE) armed with a non-alpha IL-2 variant (IL-2v), which...
2.
Bisht K, Merino A, Igarashi R, Gauthier L, Chiron M, Desjonqueres A, et al.
Exp Hematol Oncol
. 2024 Nov;
13(1):114.
PMID: 39538354
Despite therapeutic advancements, multiple myeloma (MM) remains incurable. NK cells have emerged as a promising option for the treatment of MM. NK cells are heterogenous and typically classified based on...
3.
Fenis A, Demaria O, Gauthier L, Vivier E, Narni-Mancinelli E
Nat Rev Immunol
. 2024 Jan;
24(7):471-486.
PMID: 38273127
There have been major advances in the immunotherapy of cancer in recent years, including the development of T cell engagers - antibodies engineered to redirect T cells to recognize and...
4.
Blery M, Mrabet-Kraiem M, Morel A, Lhospice F, Bregeon D, Bonnafous C, et al.
Open Res Eur
. 2023 Aug;
1:107.
PMID: 35967081
MICA and MICB are tightly regulated stress-induced proteins that trigger the immune system by binding to the activating receptor NKG2D on cytotoxic lymphocytes. MICA and MICB are highly polymorphic molecules...
5.
Decroos A, Cheminant M, Bruneau J, Carras S, Parinet V, Pelletier L, et al.
Haematologica
. 2023 May;
108(10):2830-2836.
PMID: 37165836
No abstract available.
6.
Gauthier L, Virone-Oddos A, Beninga J, Rossi B, Nicolazzi C, Amara C, et al.
Nat Biotechnol
. 2023 Jan;
41(9):1296-1306.
PMID: 36635380
CD123, the alpha chain of the IL-3 receptor, is an attractive target for acute myeloid leukemia (AML) treatment. However, cytotoxic antibodies or T cell engagers targeting CD123 had insufficient efficacy...
7.
Grossar D, Haynes E, Budge G, Parejo M, Gauthier L, Charriere J, et al.
J Invertebr Pathol
. 2022 Dec;
196:107867.
PMID: 36503887
European foulbrood (EFB) is a honey bee brood disease caused by the bacterium Melissococcus plutonius. Large-scale EFB outbreaks have been reported in several countries in recent decades, which entail costly...
8.
Demaria O, Gauthier L, Vetizou M, Alvarez A, Vagne C, Habif G, et al.
Cell Rep Med
. 2022 Oct;
3(10):100783.
PMID: 36260981
Harnessing innate immunity is emerging as a promising therapeutic approach in cancer. We report here the design of tetraspecific molecules engaging natural killer (NK) cell-activating receptors NKp46 and CD16a, the...
9.
Colomar-Carando N, Gauthier L, Merli P, Loiacono F, Canevali P, Falco M, et al.
Cancer Immunol Res
. 2022 Jan;
10(3):291-302.
PMID: 35078821
Natural killer (NK) cells represent a promising cell type in antitumor immunotherapy for efficacy and safety, particularly in the treatment of hematologic malignancies. NK cells have been shown to exert...
10.
Klein E, Malecaze F, Bart V, Barnoud A, Levy P, Gauthier L, et al.
J Cataract Refract Surg
. 2021 Aug;
48(4):435-442.
PMID: 34417777
Purpose: To assess a new polynomial regression formula integrating the refractive prediction error of the first-operated eye to improve the intraocular lens power calculation of the second eye in cataract...