Laurence J Seabrook
Overview
Explore the profile of Laurence J Seabrook including associated specialties, affiliations and a list of published articles.
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3
Citations
12
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Recent Articles
1.
Seabrook L, Franco C, Loy C, Osman J, Fredlender C, Zimak J, et al.
Nat Chem Biol
. 2024 Oct;
20(12):1566-1576.
PMID: 39414979
A paradigm shift in drug development is the discovery of small molecules that harness the ubiquitin-proteasomal pathway to eliminate pathogenic proteins. Here we provide a modality for targeted protein degradation...
2.
Franco C, Seabrook L, Nguyen S, Yang Y, Campos M, Fan Q, et al.
Sci Adv
. 2023 Sep;
9(36):eadi2232.
PMID: 37682999
Vitamin B is a vital micronutrient across cell types and tissues, and dysregulated B levels contribute to human disease. Despite its importance, how B vitamer levels are regulated is not...
3.
Franco C, Seabrook L, Nguyen S, Leonard J, Albrecht L
Metabolites
. 2022 Oct;
12(10).
PMID: 36295863
Vitamin B micronutrients are essential regulators of one carbon metabolism that ensures human health. Vitamin B9, or folate, lies at the heart of the folate cycle and converges with the...