Lauren V Albrecht
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Explore the profile of Lauren V Albrecht including associated specialties, affiliations and a list of published articles.
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16
Citations
310
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Recent Articles
1.
Seabrook L, Franco C, Loy C, Osman J, Fredlender C, Zimak J, et al.
Nat Chem Biol
. 2024 Oct;
20(12):1566-1576.
PMID: 39414979
A paradigm shift in drug development is the discovery of small molecules that harness the ubiquitin-proteasomal pathway to eliminate pathogenic proteins. Here we provide a modality for targeted protein degradation...
2.
Pereira R, Noche K, Gales B, Chen Z, Salusky I, Albrecht L
Children (Basel)
. 2024 Jul;
11(7).
PMID: 39062269
Background: Idiopathic juvenile osteoporosis (IJO) is a rare condition characterized by low bone mass that can increase the risk of fractures in children. Treatment options for these patients are limited...
3.
Campos M, Albrecht L
Cancers (Basel)
. 2024 Jan;
16(1).
PMID: 38201444
Glycolysis is the central metabolic pathway across all kingdoms of life. Intensive research efforts have been devoted to understanding the tightly orchestrated processes of converting glucose into energy in health...
4.
Laster M, Pereira R, Noche K, Gales B, Salusky I, Albrecht L
Nutrients
. 2023 Oct;
15(19).
PMID: 37836411
The pathophysiology of chronic kidney disease-mineral and bone disorder (CKD-MBD) is not well understood. Specific factors secreted by osteocytes are elevated in the serum of adults and pediatric patients with...
5.
Franco C, Seabrook L, Nguyen S, Yang Y, Campos M, Fan Q, et al.
Sci Adv
. 2023 Sep;
9(36):eadi2232.
PMID: 37682999
Vitamin B is a vital micronutrient across cell types and tissues, and dysregulated B levels contribute to human disease. Despite its importance, how B vitamer levels are regulated is not...
6.
Albrecht L, Pereira R, Salusky I
Kidney Int
. 2023 Aug;
104(5):910-915.
PMID: 37648154
Osteocytes are the most abundant type of bone cell and play crucial roles in bone health. Osteocytes sense mechanical stress and orchestrate osteoblasts and osteoclasts to maintain bone density and...
7.
Franco C, Seabrook L, Nguyen S, Leonard J, Albrecht L
Metabolites
. 2022 Oct;
12(10).
PMID: 36295863
Vitamin B micronutrients are essential regulators of one carbon metabolism that ensures human health. Vitamin B9, or folate, lies at the heart of the folate cycle and converges with the...
8.
Franco C, Noe M, Albrecht L
Front Endocrinol (Lausanne)
. 2022 May;
13:887037.
PMID: 35600583
A fundamental question in cell biology underlies how nutrients are regenerated to maintain and renew tissues. Physiologically, the canonical Wnt signaling is a vital pathway for cell growth, tissue remodeling,...
9.
Albrecht L, Tejeda-Munoz N, De Robertis E
Annu Rev Cell Dev Biol
. 2021 Jul;
37:369-389.
PMID: 34196570
Wnt signaling has multiple functions beyond the transcriptional effects of β-catenin stabilization. We review recent investigations that uncover new cell physiological effects through the regulation of Wnt receptor endocytosis, Wnt-induced...
10.
Pereira R, Gitomer B, Chonchol M, Harris P, Noche K, Salusky I, et al.
JBMR Plus
. 2021 Apr;
5(4):e10464.
PMID: 33869988
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of chronic kidney disease (CKD) and leads to a specific type of bone disease. The primary cilium is...