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Lauren Zebertavage

Explore the profile of Lauren Zebertavage including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 154
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Recent Articles
1.
Zebertavage L, Schopf A, Nielsen M, Matthews J, Erbe A, Aiken T, et al.
J Clin Med . 2024 May; 13(9). PMID: 38731089
: Incorporating GD2-targeting monoclonal antibody into post-consolidation maintenance therapy has improved survival for children with high-risk neuroblastoma. However, ~50% of patients do not respond to, or relapse following, initial treatment....
2.
Medler T, Kramer G, Bambina S, Gunderson A, Alice A, Blair T, et al.
Sci Rep . 2023 Apr; 13(1):6277. PMID: 37072485
Tissue resident memory (Trm) CD8 T cells infiltrating tumors represent an enriched population of tumor antigen-specific T cells, and their presence is associated with improved outcomes in patients. Using genetically...
3.
Aiken T, Erbe A, Zebertavage L, Komjathy D, Feils A, Rodriguez M, et al.
J Immunother Cancer . 2022 May; 10(5). PMID: 35618290
Background: Most pediatric cancers are considered immunologically cold with relatively few responding to immune checkpoint inhibition. We recently described an effective combination radio-immunotherapy treatment regimen ( ombination daptive- nnate immunotherapy...
4.
Blair T, Alice A, Zebertavage L, Crittenden M, Gough M
Front Oncol . 2021 May; 11:653625. PMID: 33968757
Analysis of tumor infiltration using conventional methods reveals a snapshot view of lymphocyte interactions with the tumor environment. However, lymphocytes have the unique capacity for continued recirculation, exploring varied tissues...
5.
Gunderson A, Yamazaki T, McCarty K, Phillips M, Alice A, Bambina S, et al.
PLoS One . 2019 Feb; 14(2):e0211117. PMID: 30726287
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a fibrotic stroma with a poor lymphocyte infiltrate, in part driven by cancer-associated fibroblasts (CAFs). CAFs, which express fibroblast activation protein (FAP), contribute...
6.
Zebertavage L, Bambina S, Shugart J, Alice A, Zens K, Lauer P, et al.
PLoS One . 2019 Jan; 14(1):e0209153. PMID: 30601871
Dysregulated signaling via the epidermal growth factor receptor (EGFR)-family is believed to contribute to the progression of a diverse array of cancers. The most common variant of EGFR is EGFRvIII,...
7.
Crittenden M, Zebertavage L, Kramer G, Bambina S, Friedman D, Troesch V, et al.
Sci Rep . 2018 May; 8(1):7012. PMID: 29725089
Radiation therapy is a source of tumor antigen release that has the potential to serve as an endogenous tumor vaccination event. In preclinical models radiation therapy synergizes with checkpoint inhibitors...