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Lauren Zasadil

Explore the profile of Lauren Zasadil including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 280
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Recent Articles
1.
Trakala M, Aggarwal M, Sniffen C, Zasadil L, Carroll A, Ma D, et al.
Genes Dev . 2021 Jul; 35(15-16):1079-1092. PMID: 34266888
Chromosome gains and losses are a frequent feature of human cancers. However, how these aberrations can outweigh the detrimental effects of aneuploidy remains unclear. An initial comparison of existing chromosomal...
2.
Santaguida S, Richardson A, Iyer D, MSaad O, Zasadil L, Knouse K, et al.
Dev Cell . 2017 Jun; 41(6):638-651.e5. PMID: 28633018
Aneuploidy, a state of karyotype imbalance, is a hallmark of cancer. Changes in chromosome copy number have been proposed to drive disease by modulating the dosage of cancer driver genes...
3.
Yoo S, Lam P, Eichelberg M, Zasadil L, Bement W, Huttenlocher A
J Cell Sci . 2012 Sep; 125(Pt 23):5702-10. PMID: 22992461
Microtubules control cell motility by positively regulating polarization in many cell types. However, how microtubules regulate leukocyte migration is not well understood, particularly in living organisms. Here we exploited the...
4.
Bolinger C, Zasadil L, Rizaldy R, Hildebrand J
Dev Dyn . 2010 Jun; 239(7):2078-93. PMID: 20549743
Vertebrate Shroom proteins define cytoskeletal organization and cellular architecture by binding directly to F-actin and Rho-kinase and spatially regulating the activity of nonmuscle myosin II (myosin II). Here, we report...