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Lauren Yocum

Explore the profile of Lauren Yocum including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 166
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Recent Articles
1.
Makarcyzk M, Li Z, Yu I, Yagi H, Zhang X, Yocum L, et al.
J Vis Exp . 2023 Feb; (191). PMID: 36779602
The high prevalence of debilitating joint diseases like osteoarthritis (OA) poses a high socioeconomic burden. Currently, the available drugs that target joint disorders are mostly palliative. The unmet need for...
2.
Li Z, Lin Z, Liu S, Yagi H, Zhang X, Yocum L, et al.
Adv Sci (Weinh) . 2022 Apr; 9(21):e2105909. PMID: 35436042
Diseases of the knee joint such as osteoarthritis (OA) affect all joint elements. An in vitro human cell-derived microphysiological system capable of simulating intraarticular tissue crosstalk is desirable for studying...
3.
Li Z, Xiang S, Lin Z, Li E, Yagi H, Cao G, et al.
Biomaterials . 2021 Aug; 277:121082. PMID: 34464823
Biomaterials that can harness the intrinsic osteogenic potential of stem cells offer a promising strategy to accelerate bone regeneration and repair. Previously, we had used methacrylated gelatin (GelMA)-based scaffolds to...
4.
He Y, Yocum L, Alexander P, Jurczak M, Lin H
Front Pharmacol . 2021 Jul; 12:703847. PMID: 34220525
Physiological mechanical stimulation has been shown to promote chondrogenesis, but excessive mechanical loading results in cartilage degradation. Currently, the underlying mechanotransduction pathways in the context of physiological and injurious loading...
5.
He Y, Li Z, Alexander P, Ocasio-Nieves B, Yocum L, Lin H, et al.
Biology (Basel) . 2020 Aug; 9(8). PMID: 32751156
As the most common chronic degenerative joint disease, osteoarthritis (OA) is the leading cause of pain and physical disability, affecting millions of people worldwide. Mainly characterized by articular cartilage degradation,...