Lauren M Ramsay
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Explore the profile of Lauren M Ramsay including associated specialties, affiliations and a list of published articles.
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9
Citations
72
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Recent Articles
1.
Ramsay L, Cermak N, Dada O, Dovichi N
Anal Bioanal Chem
. 2011 Apr;
400(7):2025-30.
PMID: 21461616
Capillary isoelectric focusing tends to suffer from poor reproducibility, particularly for the analysis of complex protein samples from cellular or tissue homogenates. This poor reproducibility appears to be associated with...
2.
Dickerson J, Ramsay L, Dada O, Cermak N, Dovichi N
Electrophoresis
. 2010 Jul;
31(15):2650-4.
PMID: 20603830
CIEF and CZE are coupled with LIF detection to create an ultrasensitive 2-D separation method for proteins. In this method, two capillaries are joined through a buffer-filled interface. Separate power...
3.
Dada O, Ramsay L, Dickerson J, Cermak N, Jiang R, Zhu C, et al.
Anal Bioanal Chem
. 2010 Mar;
397(8):3305-10.
PMID: 20336452
We report a multiplexed capillary electrophoresis system employing an array of 32 capillaries with a micromachined sheath-flow cuvette as the detection chamber. The sample streams were simultaneously excited with a...
4.
Ramsay L, Dickerson J, Dada O, Dovichi N
Anal Chem
. 2009 Feb;
81(5):1741-6.
PMID: 19206532
Fluorescence tends to produce the lowest detection limits for most forms of capillary electrophoresis. Two issues have discouraged its use in capillary isoelectric focusing. The first issue is fluorescent labeling...
5.
Ramsay L, Dickerson J, Dovichi N
Electrophoresis
. 2009 Feb;
30(2):297-302.
PMID: 19204946
We have coupled CIEF with an LIF detector that is based on a post-column sheath flow cuvette. We employed Chromeo P503 as a fluorogenic reagent to label proteins before analysis....
6.
Turner E, Dickerson J, Ramsay L, Swearingen K, Wojcik R, Dovichi N
J Chromatogr A
. 2008 May;
1194(2):253-6.
PMID: 18482729
The spectroscopic and electrophoretic properties of proteins labeled with Chromeo P503 were investigated. Its photobleaching characteristics were determined by continually infusing Chromeo P503-labeled alpha-lactalbumin into a sheath-flow cuvette and monitored...
7.
Swearingen K, Dickerson J, Turner E, Ramsay L, Wojcik R, Dovichi N
J Chromatogr A
. 2008 May;
1194(2):249-52.
PMID: 18479693
The fluorogenic reagent Chromeo P465 is considered for the analysis of proteins by capillary electrophoresis with laser-induced fluorescence detection. The reagent was first used to label alpha-lactalbumin; the product was...
8.
Wojcik R, Swearingen K, Dickerson J, Turner E, Ramsay L, Dovichi N
J Chromatogr A
. 2008 May;
1194(2):243-8.
PMID: 18479688
3-(2-Furoyl)quinoline-2-carboxaldehyde (FQ), Chromeo P465, and Chromeo P503 are weakly fluorescent reagents that react with primary amines to produce fluorescent products. We studied the reaction of these reagents with alpha-lactalbumin by...
9.
Caulum M, Murphy B, Ramsay L, Henry C
Anal Chem
. 2007 Jun;
79(14):5249-56.
PMID: 17566984
Biomarkers provide clinicians with an important tool for disease assessment. Many different biomarkers have been discovered, but few of them suffice as stand-alone indicators for disease presence or prognosis. Because...