Lauren Ames
Overview
Explore the profile of Lauren Ames including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
301
Followers
0
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Recent Articles
1.
Quach D, Sharp M, Ahmed S, Ames L, Bhagwat A, Deshpande A, et al.
Proc Natl Acad Sci U S A
. 2025 Feb;
122(6):e2419813122.
PMID: 39913203
Tuberculosis (TB), caused by , remains a significant global health threat, affecting an estimated 10.6 million people in 2022. The emergence of multidrug resistant and extensively drug resistant strains necessitates...
2.
Allen R, Ames L, Baldin V, Butts A, Henry K, Durst G, et al.
Antimicrob Agents Chemother
. 2024 Sep;
68(11):e0103724.
PMID: 39324799
We investigated the mechanism of action of an arylsulfonamide with whole-cell activity against . We newly synthesized the molecule and confirmed it had activity against both extracellular and intracellular bacilli....
3.
Kounatidis I, Ames L, Mistry R, Ho H, Haynes K, Ligoxygakis P
G3 (Bethesda)
. 2018 Mar;
8(5):1637-1647.
PMID: 29535147
() forms part of the normal human gut microbiota but can cause life-threatening invasive infections in immune-compromised individuals. displays high resistance to common azole antifungals, which necessitates new treatments. In...
4.
Ames L, Duxbury S, Pawlowska B, Ho H, Haynes K, Bates S
Virulence
. 2017 Jun;
8(8):1909-1917.
PMID: 28658597
No abstract available.
5.
Holland L, Schroder M, Turner S, Taff H, Andes D, Grozer Z, et al.
PLoS Pathog
. 2014 Sep;
10(9):e1004365.
PMID: 25233198
Candida parapsilosis and Candida albicans are human fungal pathogens that belong to the CTG clade in the Saccharomycotina. In contrast to C. albicans, relatively little is known about the virulence...
6.
Schwarzmuller T, Ma B, Hiller E, Istel F, Tscherner M, Brunke S, et al.
PLoS Pathog
. 2014 Jun;
10(6):e1004211.
PMID: 24945925
The opportunistic fungal pathogen Candida glabrata is a frequent cause of candidiasis, causing infections ranging from superficial to life-threatening disseminated disease. The inherent tolerance of C. glabrata to azole drugs...
7.
Kasper L, Seider K, Gerwien F, Allert S, Brunke S, Schwarzmuller T, et al.
PLoS One
. 2014 May;
9(5):e96015.
PMID: 24789333
Candida glabrata currently ranks as the second most frequent cause of invasive candidiasis. Our previous work has shown that C. glabrata is adapted to intracellular survival in macrophages and replicates...
8.
Kaloriti D, Tillmann A, Cook E, Jacobsen M, You T, Lenardon M, et al.
Med Mycol
. 2012 Apr;
50(7):699-709.
PMID: 22463109
Pathogenic microbes exist in dynamic niches and have evolved robust adaptive responses to promote survival in their hosts. The major fungal pathogens of humans, Candida albicans and Candida glabrata, are...