Lauren A ODonnell
Overview
Explore the profile of Lauren A ODonnell including associated specialties, affiliations and a list of published articles.
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29
Citations
305
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Recent Articles
1.
Kushner D, Breitbart M, Debbink K, Ferran M, Johnson D, Newcomb L, et al.
J Microbiol Biol Educ
. 2024 Oct;
25(3):e0010024.
PMID: 39431826
It has become increasingly important for microbiology educators to help students learn critical concepts of the discipline. This is particularly true in virology, where current challenges include increasing rates of...
2.
Kamte Y, Chandwani M, London N, Potosnak C, Leak R, ODonnell L
J Neurochem
. 2023 Aug;
166(5):809-829.
PMID: 37530081
Viral infections of the central nervous system (CNS) often cause worse neurological outcomes in younger hosts. Throughout childhood, the brain undergoes extensive development and refinement to produce functional neural networks....
3.
Chandwani M, Kamte Y, Singh V, Hemerson M, Michaels A, Leak R, et al.
Brain Behav Immun
. 2023 Jul;
114:61-77.
PMID: 37516388
Viruses induce a wide range of neurological sequelae through the dysfunction and death of infected cells and persistent inflammation in the brain. Neural stem cells (NSCs) are often disturbed during...
4.
Bhatia T, Jamenis A, Abbas M, Clark R, Miner K, Chandwani M, et al.
Neurobiol Dis
. 2023 Jun;
184:106196.
PMID: 37315905
Reactive microglia are observed with aging and in Lewy body disorders, including within the olfactory bulb of men with Parkinson's disease. However, the functional impact of microglia in these disorders...
5.
Kushner D, Cline T, Danthi P, Debbink K, Ferran M, Flenniken M, et al.
J Virol
. 2022 Sep;
96(18):e0130522.
PMID: 36094313
Curriculum guidelines for virology are needed to best guide student learning due to the continuous and ever-increasing volume of virology information, the need to ensure that undergraduate and graduate students...
6.
Khare P, Dave K, Kamte Y, Manoharan M, ODonnell L, Manickam D
AAPS J
. 2021 Dec;
24(1):8.
PMID: 34873640
Lipidoid nanoparticles (LNPs) are the delivery platform in Onpattro, the first FDA-approved siRNA drug. LNPs are also the carriers in the Pfizer-BioNTech and Moderna COVID-19 mRNA vaccines. While these applications...
7.
Kamte Y, Chandwani M, Michaels A, ODonnell L
Viruses
. 2021 Aug;
13(8).
PMID: 34452333
Viruses that infect the central nervous system (CNS) are associated with developmental abnormalities as well as neuropsychiatric and degenerative conditions. Many of these viruses such as Zika virus (ZIKV), cytomegalovirus...
8.
Vasa D, Bakri Z, Donovan M, ODonnell L, Wildfong P
Pharmaceutics
. 2021 Aug;
13(8).
PMID: 34452087
Ribavirin is a water-soluble antiviral compound which, owing to its inability to cross the blood-brain barrier, has limited effectiveness in treating viruses affecting the central nervous system. Direct nose-to-brain delivery...
9.
Creisher P, Chandwani M, Kamte Y, Covvey J, Ganesan P, ODonnell L
Dev Neurobiol
. 2020 Sep;
80(7-8):213-228.
PMID: 32866337
Viral infections of the central nervous system (CNS) often cause disease in an age-dependent manner, with greater neuropathology during the fetal and neonatal periods. Transgenic CD46+ mice model these age-dependent...
10.
Kennedy D, Beckett R, ODonnell L
Am J Pharm Educ
. 2020 Apr;
84(1):7702.
PMID: 32292199
Most pharmacy faculty members are more confident in their foundation as research scientists or clinical pharmacists than with the scholarship of teaching and learning (SoTL). However, many wish to enter...