Laura Thirouard
Overview
Explore the profile of Laura Thirouard including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
90
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0
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Recent Articles
1.
Garcia M, Holota H, De Haze A, Saru J, Sanchez P, Battistelli E, et al.
J Biol Chem
. 2024 Nov;
301(1):108022.
PMID: 39608717
Farnesoid X receptor α (FXRα, NR1H4) is a bile acid-activated nuclear receptor that regulates the expression of glycolytic and lipogenic target genes by interacting with the 9-cis-retinoic acid receptor α...
2.
Durand R, Bellanger C, Descamps G, Dousset C, Maiga S, Derrien J, et al.
Hemasphere
. 2024 Oct;
8(10):e70016.
PMID: 39380841
In multiple myeloma, as in B-cell malignancies, mono- and especially bi-allelic gene inactivation is a high-risk factor for treatment resistance, and there are currently no therapies specifically targeting p53 deficiency....
3.
Monrose M, Holota H, Martinez G, Damon-Soubeyrand C, Thirouard L, Martinot E, et al.
Adv Sci (Weinh)
. 2024 Sep;
11(43):e2402082.
PMID: 39318179
Male sexual function can be disrupted by exposure to exogenous compounds that cause testicular physiological alterations. The constitutive androstane receptor (Car) is a receptor for both endobiotics and xenobiotics involved...
4.
Thirouard L, Holota H, Monrose M, Garcia M, De Haze A, Damon-Soubeyrand C, et al.
Adv Sci (Weinh)
. 2022 Apr;
9(17):e2200626.
PMID: 35435331
Spermatogonial stem cells regenerate and maintain spermatogenesis throughout life, making testis a good model for studying stem cell biology. The effects of chemotherapy on fertility have been well-documented previously. This...
5.
Thirouard L, Holota H, Monrose M, Garcia M, De Haze A, Saru J, et al.
Cells
. 2021 Sep;
10(9).
PMID: 34572051
Spermatogenesis is a process within the testis that leads to the production of spermatozoa. It is based on a population of spermatogonial stem cells, which have the capacity to self-renew...
6.
Martinot E, Thirouard L, Holota H, Monrose M, Garcia M, Beaudoin C, et al.
Gut
. 2021 May;
71(4):844-845.
PMID: 33985968
No abstract available.
7.
Holota H, Thirouard L, Monrose M, Garcia M, De Haze A, Saru J, et al.
Mol Cell Endocrinol
. 2020 Aug;
518:110995.
PMID: 32827571
The hypothalamic-pituitary axis exert a major control over endocrine and exocrine testicular functions. The hypothalamic-pituitary axis corresponds to a cascade with the Gonadotropin Releasing Hormone secreted by the hypothalamus, which...
8.
Holota H, Thirouard L, Garcia M, Monrose M, De Haze A, Saru J, et al.
J Steroid Biochem Mol Biol
. 2019 Aug;
194:105460.
PMID: 31470110
The bile acid receptor Farnesoid-X-Receptor alpha (FXRα), a member of the nuclear receptor superfamily, is well known for its roles in the enterohepatic tract. In addition, FXRα regulates testicular physiology...
9.
Garcia M, Thirouard L, Monrose M, Holota H, De Haze A, Caira F, et al.
Cell Mol Life Sci
. 2019 Aug;
76(24):4849-4859.
PMID: 31407019
The farnesoid-X-receptorα (FXRα; NR1H4) is one of the main bile acid (BA) receptors. During the last decades, through the use of pharmalogical approaches and transgenic mouse models, it has been...
10.
Garcia M, Thirouard L, Sedes L, Monrose M, Holota H, Caira F, et al.
Int J Mol Sci
. 2018 Nov;
19(11).
PMID: 30453651
Structural and functional studies have provided numerous insights over the past years on how members of the nuclear hormone receptor superfamily tightly regulate the expression of drug-metabolizing enzymes and transporters....