Laura Senovilla
Overview
Explore the profile of Laura Senovilla including associated specialties, affiliations and a list of published articles.
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Articles
95
Citations
5379
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0
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Recent Articles
1.
Mondragon L, Shen S, Senovilla L
Front Oncol
. 2024 Dec;
14:1504738.
PMID: 39629001
No abstract available.
2.
de la Puente-Aldea J, Lopez-Llanos O, Horrillo D, Marcos-Sanchez H, Sanz-Ballesteros S, Franco R, et al.
Int J Mol Sci
. 2024 Nov;
25(22).
PMID: 39596384
The classical function of the mineralocorticoid receptor (MR) is to maintain electrolytic homeostasis and control extracellular volume and blood pressure. The MR is expressed in the central nervous system (CNS)...
3.
Gonzalez-Gutierrez L, Motino O, Barriuso D, de la Puente-Aldea J, Alvarez-Frutos L, Kroemer G, et al.
Int J Mol Sci
. 2024 Aug;
25(16).
PMID: 39201522
Colorectal cancer (CRC) affects approximately 2 million people worldwide. Obesity is the major risk factor for CRC. In addition, obesity contributes to a chronic inflammatory stage that enhances tumor progression...
4.
Alvarez-Frutos L, Barriuso D, Duran M, Infante M, Kroemer G, Palacios-Ramirez R, et al.
Front Oncol
. 2024 Jan;
13:1292046.
PMID: 38169859
Breast cancer is the most common malignant neoplasm in women. Despite progress to date, 700,000 women worldwide died of this disease in 2020. Apparently, the prognostic markers currently used in...
5.
Barriuso D, Alvarez-Frutos L, Gonzalez-Gutierrez L, Motino O, Kroemer G, Palacios-Ramirez R, et al.
Int J Mol Sci
. 2023 Apr;
24(7).
PMID: 37047342
The B-cell lymphoma 2 (Bcl-2) family of proteins is the main regulator of apoptosis. However, multiple emerging evidence has revealed that Bcl-2 family proteins are also involved in cellular senescence....
6.
Motino O, Lambertucci F, Anagnostopoulos G, Li S, Nah J, Castoldi F, et al.
Proc Natl Acad Sci U S A
. 2022 Oct;
119(41):e2207344119.
PMID: 36191214
Acyl-coenzyme A (CoA)-binding protein (ACBP), also known as diazepam-binding inhibitor (DBI), is an extracellular feedback regulator of autophagy. Here, we report that injection of a monoclonal antibody neutralizing ACBP/DBI (α-DBI)...
7.
Deng J, Gutierrez L, Stoll G, Motino O, Martins I, Nunez L, et al.
Cell Death Dis
. 2021 Nov;
12(11):1039.
PMID: 34725331
Pro-apoptotic multi-domain proteins of the BCL2 family such as BAX and BAK are well known for their important role in the induction of mitochondrial outer membrane permeabilization (MOMP), which is...
8.
Deng J, Tian A, Pan H, Sauvat A, Leduc M, Liu P, et al.
Cell Death Dis
. 2021 Oct;
12(11):978.
PMID: 34675191
Colorectal cancers (CRC) can be classified into four consensus molecular subtypes (CMS), among which CMS1 has the best prognosis, contrasting with CMS4 that has the worst outcome. CMS4 CRC is...
9.
Bravo-San Pedro J, Kepp O, Sauvat A, Rello-Varona S, Kroemer G, Senovilla L
Methods Mol Biol
. 2021 Mar;
2267:227-239.
PMID: 33786796
Mitotic catastrophe (MC) is a cell death modality induced by DNA damage that involves the activation of cell cycle checkpoints such as the "DNA structure checkpoint" and "spindle assembly checkpoint"...
10.
Humeau J, Bezu L, Kepp O, Senovilla L, Liu P, Kroemer G
Methods Mol Biol
. 2021 Mar;
2267:217-226.
PMID: 33786795
Mitotic catastrophe is an oncosuppressive mechanism that drives cells toward senescence or death when an error occurs during mitosis. Eukaryotic cells have developed adaptive signaling pathways to cope with stress....