Laura R Caggiano
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Explore the profile of Laura R Caggiano including associated specialties, affiliations and a list of published articles.
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8
Citations
30
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Recent Articles
1.
Philip J, Caneba C, Caggiano L, Prakash N, Cheng T, Barlow K, et al.
bioRxiv
. 2025 Feb;
PMID: 39975245
Hypoxic pulmonary hypertension (HPH) develops in association with diseases characterized by low oxygen levels leading to pulmonary artery (PA) narrowing and death. Hypoxia has been linked to increased PA collagen...
2.
Mallikarjun V, Yin B, Caggiano L, Blimbaum S, Pavelec C, Holmes J, et al.
J Mol Cell Cardiol
. 2023 Nov;
186:1-15.
PMID: 37951204
Myocardial infarction (MI) results from occlusion of blood supply to the heart muscle causing death of cardiac muscle cells. Following myocardial infarction (MI), extracellular matrix deposition and scar formation mechanically...
3.
Caggiano L, Chesler N
Am J Respir Cell Mol Biol
. 2023 Feb;
68(5):478-479.
PMID: 36821488
No abstract available.
4.
Allen B, Frye H, Ramanathan R, Caggiano L, Tabima D, Chesler N, et al.
J Am Heart Assoc
. 2023 Feb;
12(3):e028121.
PMID: 36734341
Combined pre-/postcapillary pulmonary hypertension (Cpc-PH), a complication of left heart failure, is associated with higher mortality rates than isolated postcapillary pulmonary hypertension alone. Currently, knowledge gaps persist on the mechanisms...
5.
Cheng T, Tabima D, Caggiano L, Frump A, Hacker T, Eickhoff J, et al.
J Appl Physiol (1985)
. 2022 Feb;
132(3):888-901.
PMID: 35112927
With severe right ventricular (RV) pressure overload, women demonstrate better clinical outcomes compared with men. The mechanoenergetic mechanisms underlying this protective effect, and their dependence on female endogenous sex hormones,...
6.
Caggiano L, Holmes J
J Elast
. 2022 Jan;
145(1-2):321-337.
PMID: 35095176
The mechanics of most soft tissues in the human body are determined by the organization of their collagen fibers. Predicting how mechanics will change during growth and remodeling of those...
7.
Caggiano L, Holmes J, Witzenburg C
J Mol Cell Cardiol
. 2021 Nov;
163:156-166.
PMID: 34756992
Ventricular enlargement and heart failure are common in patients who survive a myocardial infarction (MI). There is striking variability in the degree of post-infarction ventricular remodeling, however, and no one...
8.
Yin B, Caggiano L, Li R, McGowan E, Holmes J, Ewald S
J Proteome Res
. 2021 Aug;
20(9):4543-4552.
PMID: 34436902
Tissue microenvironment properties like blood flow, extracellular matrix, or proximity to immune-infiltrate are important regulators of cell biology. However, methods to study regional protein expression in the native tissue environment...
9.
Caggiano L, Lee J, Holmes J
Am J Physiol Heart Circ Physiol
. 2018 Jul;
315(4):H1041-H1050.
PMID: 30028201
Previous studies have suggested that the composition and global mechanical properties of the scar tissue that forms after a myocardial infarction (MI) are key determinants of long-term survival, and emerging...