Laura M McKay
Overview
Explore the profile of Laura M McKay including associated specialties, affiliations and a list of published articles.
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4
Citations
198
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0
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Recent Articles
1.
Ney G, Yang K, Ng V, Liu L, Zhao M, Kuk W, et al.
Cancer Res
. 2021 Jan;
81(5):1240-1251.
PMID: 33441311
Leukemic relapse is believed to be driven by transformed hematopoietic stem cells (HSC) that harbor oncogenic mutations or have lost tumor suppressor function. Recent comprehensive sequencing studies have shown that...
2.
Phillips A, Boghaert E, Vaidya K, Mitten M, Norvell S, Falls H, et al.
Mol Cancer Ther
. 2016 Feb;
15(4):661-9.
PMID: 26846818
Targeting tumor-overexpressed EGFR with an antibody-drug conjugate (ADC) is an attractive therapeutic strategy; however, normal tissue expression represents a significant toxicity risk. The anti-EGFR antibody ABT-806 targets a unique tumor-specific...
3.
Yap R, Veliceasa D, Emmenegger U, Kerbel R, McKay L, Henkin J, et al.
Clin Cancer Res
. 2005 Sep;
11(18):6678-85.
PMID: 16166447
Blocking angiogenesis is a promising approach in cancer therapy. Natural inhibitors of angiogenesis and derivatives induce receptor-mediated signals, which often result in the endothelial cell death. Low-dose chemotherapy, given at...
4.
Haviv F, Bradley M, Kalvin D, Schneider A, Davidson D, Majest S, et al.
J Med Chem
. 2005 Apr;
48(8):2838-46.
PMID: 15828822
The heptapeptide 1, NAc-Gly-Val-DIle-Thr-Arg-Ile-ArgNHEt, a structurally modified fragment derived from the second type-1 repeat of thrombospondin-1 (TSP-1), is known to possess antiangiogenic activity. However, therapeutic utility could not be demonstrated...