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Laura Formentini

Explore the profile of Laura Formentini including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 1060
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Recent Articles
1.
Albericio G, Higuera M, Araque P, Sanchez C, Herrero D, Garcia-Brenes M, et al.
Int J Mol Sci . 2024 Aug; 25(16). PMID: 39201501
The adult mammalian heart has been demonstrated to be endowed with low but real turnover capacity, especially for cardiomyocytes, the key functional cell type. The source, however, of that turnover...
2.
Herrero Martin J, Salegi Ansa B, Alvarez-Rivera G, Dominguez-Zorita S, Rodriguez-Pombo P, Perez B, et al.
Nat Metab . 2024 Jan; 6(2):209-225. PMID: 38243131
Coenzyme Q (Q) is a key lipid electron transporter, but several aspects of its biosynthesis and redox homeostasis remain undefined. Various flavoproteins reduce ubiquinone (oxidized form of Q) to ubiquinol...
3.
Sanchez-Gonzalez C, Herrero Martin J, Salegi Ansa B, Nunez de Arenas C, Stancic B, Pereira M, et al.
Cell Death Dis . 2022 Jun; 13(6):561. PMID: 35732639
Tubular aggregates (TA) are honeycomb-like arrays of sarcoplasmic-reticulum (SR) tubules affecting aged glycolytic fibers of male individuals and inducing severe sarcomere disorganization and muscular pain. TA develop in skeletal muscle...
4.
Sanchez-Gonzalez C, Formentini L
STAR Protoc . 2021 Aug; 2(3):100735. PMID: 34430910
Depending on metabolic requirements, skeletal muscle mitochondria integrate O consumption and ATP production with lipid, glucose, or amino acid metabolism. Free fatty acids (FFAs) are the main source of energy...
5.
Alcover-Sanchez B, Garcia-Martin G, Escudero-Ramirez J, Gonzalez-Riano C, Lorenzo P, Gimenez-Cassina A, et al.
Glia . 2020 Oct; 69(3):619-637. PMID: 33010069
Fast synaptic transmission in vertebrates is critically dependent on myelin for insulation and metabolic support. Myelin is produced by oligodendrocytes (OLs) that maintain multilayered membrane compartments that wrap around axonal...
6.
Nuevo-Tapioles C, Santacatterina F, Stamatakis K, Nunez de Arenas C, Gomez de Cedron M, Formentini L, et al.
Nat Commun . 2020 Jul; 11(1):3606. PMID: 32681016
Mitochondrial metabolism has emerged as a promising target against the mechanisms of tumor growth. Herein, we have screened an FDA-approved library to identify drugs that inhibit mitochondrial respiration. The β1-blocker...
7.
Sanchez-Gonzalez C, Nuevo-Tapioles C, Herrero Martin J, Pereira M, Serrano Sanz S, Ramirez de Molina A, et al.
EMBO J . 2020 Jun; 39(14):e103812. PMID: 32488939
It is controversial whether mitochondrial dysfunction in skeletal muscle is the cause or consequence of metabolic disorders. Herein, we demonstrate that in vivo inhibition of mitochondrial ATP synthase in muscle...
8.
Montesanto A, DAquila P, Lagani V, Paparazzo E, Geracitano S, Formentini L, et al.
J Forensic Sci . 2020 May; 65(5):1424-1431. PMID: 32453457
Forensic DNA phenotyping refers to an emerging field of forensic sciences aimed at the prediction of externally visible characteristics of unknown sample donors directly from biological materials. The aging process...
9.
Giacconi R, Malavolta M, Burkle A, Moreno-Villanueva M, Franceschi C, Capri M, et al.
Nutrients . 2019 Dec; 11(12). PMID: 31817660
Alu hypomethylation promotes genomic instability and is associated with aging and age-related diseases. Dietary factors affect global DNA methylation, leading to changes in genomic stability and gene expression with an...
10.
Formentini L, Ryan A, Galvez-Santisteban M, Carter L, Taub P, Lapek Jr J, et al.
Diabetologia . 2018 Oct; 61(12):2674. PMID: 30324489
Owing to an oversight, the authors omitted to note that Dr Taub is a co-founder of and equity holder in Cardero Therapeutics.