Laura E Gleeson
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Explore the profile of Laura E Gleeson including associated specialties, affiliations and a list of published articles.
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19
Citations
1083
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Recent Articles
1.
Cox D, Connolly S, O Maoldomhnaigh C, Brugman A, Sandby Thomas O, Duffin E, et al.
Elife
. 2024 Dec;
13.
PMID: 39620891
Airway macrophages (AM) are the predominant immune cell in the lung and play a crucial role in preventing infection, making them a target for host directed therapy. Macrophage effector functions...
2.
Jameson G, Walsh A, Woods R, Batten I, Murphy D, Connolly S, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(42):e2412489121.
PMID: 39378091
Tissue-resident natural killer (trNK) cells are present in the human lung, yet their metabolic function is unknown. NK cell effector and metabolic function are intrinsically linked therefore targeting metabolism presents...
3.
Roche S, Ottewill C, Mulpeter R, Brown K, Grant C, Fraughen D, et al.
Am J Respir Crit Care Med
. 2024 Aug;
210(8):1061-1065.
PMID: 39133464
No abstract available.
4.
McNally E, Ross C, Gleeson L
Breathe (Sheff)
. 2023 Dec;
19(4):230143.
PMID: 38125799
Educational Aims: To demonstrate that pleural TB incorporates a wide spectrum of disease, ranging from self-resolving lymphocytic effusions to severe TB empyema with serious sequelae.To emphasise the high coexistence of...
5.
Smith D, Meghji J, Moonim M, Ross C, Viola P, Wickremasinghe M, et al.
Respirol Case Rep
. 2023 Oct;
11(11):e01231.
PMID: 37840600
Here we describe three cases of sarcoidosis which were diagnosed following COVID infection. Treating clinicians should consider post-COVID-19 sarcoidosis in their differential, as it represents a potentially treatable cause of...
6.
Gleeson L, Waterer G
Breathe (Sheff)
. 2022 Nov;
18(2):210171.
PMID: 36337137
Educational Aims: To recognise the growing prevalence and importance of NTM pulmonary disease globally.To identify shortfalls in current diagnostic and therapeutic strategies, and highlight the challenges that must be addressed...
7.
Gleeson L, Roche H, Sheedy F
Br J Nutr
. 2020 Sep;
125(6):628-632.
PMID: 32892755
As COVID-19 continues to spread worldwide, severe disease and mortality have been observed in obese patients. We discuss how obesity and obesity-associated factors such as ‘meta-flammation’, dietary fat intake and...
8.
Hackett E, Charles-Messance H, OLeary S, Gleeson L, Munoz-Wolf N, Case S, et al.
Cell Rep
. 2020 Jan;
30(1):124-136.e4.
PMID: 31914380
Increased glycolytic metabolism recently emerged as an essential process driving host defense against Mycobacterium tuberculosis (Mtb), but little is known about how this process is regulated during infection. Here, we...
9.
Gleeson L, Lee Y
J Bronchology Interv Pulmonol
. 2019 Dec;
27(1):1-3.
PMID: 31856010
No abstract available.
10.
Gleeson L, OLeary S, Ryan D, McLaughlin A, Sheedy F, Keane J
Am J Respir Cell Mol Biol
. 2018 Jun;
59(5):572-579.
PMID: 29944387
Smoking is a major risk factor driving the tuberculosis epidemic, and smokers' alveolar macrophages (AM) demonstrate significant immune defects after infection. Recently, macrophage glycolytic reprogramming has emerged as crucial in...