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Laura E Danielian

Explore the profile of Laura E Danielian including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 461
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Recent Articles
1.
Portley M, Sherer C, Wu T, Farren J, Danielian L, Scholz S, et al.
Ann Clin Transl Neurol . 2023 Aug; 10(10):1816-1823. PMID: 37545108
Objective: Cognitive contributions to decisional capacity are complex and not well understood. Capacity to consent for research has been linked to executive function, but executive function assessment tools are imperfect....
2.
Waugh R, Danielian L, Shoukry R, Floeter M
Neurobiol Aging . 2021 Jan; 99:1-10. PMID: 33421737
The risk for carriers of repeat expansion mutations in C9orf72 to develop amyotrophic lateral sclerosis and frontotemporal dementia increases with age. Functional magnetic resonance imaging studies have shown reduced connectivity...
3.
Clark M, Smallwood Shoukry R, Huang C, Danielian L, Bageac D, Floeter M
Amyotroph Lateral Scler Frontotemporal Degener . 2018 Oct; 19(7-8):562-569. PMID: 30299161
Objective: The clinical diagnosis of primary lateral sclerosis can only be made after upper motor neuron symptoms have progressed for several years without developing lower motor neuron signs. The goal...
4.
Floeter M, Danielian L, Braun L, Wu T
J Neurol Neurosurg Psychiatry . 2017 Oct; 89(1):53-60. PMID: 29054917
Introduction: Discrepancies between diffusion tensor imaging (DTI) findings and functional rating scales in amyotrophic lateral sclerosis (ALS) may be due to symptom heterogeneity, particularly coexisting cognitive-behavioural dysfunction affecting non-motor regions...
5.
Cardenas A, Sarlls J, Kwan J, Bageac D, Gala Z, Danielian L, et al.
Neuroimage Clin . 2017 May; 15:200-208. PMID: 28529876
Objectives: The goal of this study was to better understand the changes in tissue microstructure that underlie white matter diffusion changes in ALS patients. Methods: Diffusion tensor imaging was carried...
6.
Floeter M, Bageac D, Danielian L, Braun L, Traynor B, Kwan J
Neuroimage Clin . 2016 Dec; 12:1035-1043. PMID: 27995069
Expansion mutations in the gene may cause amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), or mixtures of the two clinical phenotypes. Different imaging findings have been described for -associated diseases...
7.
Kwan J, Meoded A, Danielian L, Wu T, Floeter M
Neuroimage Clin . 2013 Nov; 2:151-60. PMID: 24179768
Magnetic resonance imaging measures have been proposed as objective markers to study upper motor neuron loss in motor neuron disorders. Cross-sectional studies have identified imaging differences between groups of healthy...
8.
Meoded A, Kwan J, Peters T, Huey E, Danielian L, Wiggs E, et al.
Dement Geriatr Cogn Dis Extra . 2013 Sep; 3(1):233-50. PMID: 24052798
Introduction: Executive dysfunction occurs in many patients with amyotrophic lateral sclerosis (ALS), but it has not been well studied in primary lateral sclerosis (PLS). The aims of this study were...
9.
Floeter M, Danielian L, Kim Y
Restor Neurol Neurosci . 2012 Nov; 31(1):53-62. PMID: 23142814
Purpose: Learning a skilled movement is associated with more efficient use of subcortical motor circuits which can coordinate features of the movements such as the timing and patterns of activation...
10.
Kwan J, Jeong S, van Gelderen P, Deng H, Quezado M, Danielian L, et al.
PLoS One . 2012 Apr; 7(4):e35241. PMID: 22529995
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by cortical and spinal motor neuron dysfunction. Routine magnetic resonance imaging (MRI) studies have previously shown hypointense signal in the...