Laura C A Galbraith
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Explore the profile of Laura C A Galbraith including associated specialties, affiliations and a list of published articles.
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9
Citations
695
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Recent Articles
1.
Hartley A, Galbraith L, Shaw R, Tibbo A, Veeratterapillay R, Wilson L, et al.
Br J Cancer
. 2025 Jan;
PMID: 39885328
Background: Prostate cancer (PC) is the commonest male visceral cancer, and second leading cause of cancer mortality in men in the Western world. Methods: Using a forward-mutagenesis Sleeping Beauty (SB)...
2.
Ackermann T, Shokry E, Deshmukh R, Anand J, Galbraith L, Mitchell L, et al.
EMBO Mol Med
. 2024 Oct;
16(11):2749-2774.
PMID: 39433871
The limited availability of therapeutic options for patients with triple-negative breast cancer (TNBC) contributes to the high rate of metastatic recurrence and poor prognosis. Ferroptosis is a type of cell...
3.
Martinez R, Salji M, Rushworth L, Ntala C, Blanco G, Hedley A, et al.
Cancer Res
. 2021 May;
81(13):3664-3678.
PMID: 33985973
Androgen deprivation therapy (ADT) is the standard of care for treatment of nonresectable prostate cancer. Despite high treatment efficiency, most patients ultimately develop lethal castration-resistant prostate cancer (CRPC). In this...
4.
Nacke M, Sandilands E, Nikolatou K, Roman-Fernandez A, Mason S, Patel R, et al.
Nat Commun
. 2021 Mar;
12(1):1623.
PMID: 33712589
The signalling pathways underpinning cell growth and invasion use overlapping components, yet how mutually exclusive cellular responses occur is unclear. Here, we report development of 3-Dimensional culture analyses to separately...
5.
Galbraith L, Mui E, Nixon C, Hedley A, Strachan D, Mackay G, et al.
Oncogene
. 2021 Mar;
40(13):2355-2366.
PMID: 33654198
Peroxisome Proliferator-Activated Receptor Gamma (PPARG) is one of the three members of the PPAR family of transcription factors. Besides its roles in adipocyte differentiation and lipid metabolism, we recently demonstrated...
6.
Fitzsimmons L, Cartlidge R, Chang C, Sejic N, Galbraith L, Suraweera C, et al.
Cell Death Differ
. 2019 Oct;
27(5):1554-1568.
PMID: 31645677
Epstein-Barr virus (EBV), which is ubiquitous in the adult population, is causally associated with human malignancies. Like many infectious agents, EBV has evolved strategies to block host cell death, including...
7.
Bray T, Salji M, Brombin A, Perez-Lopez A, Rubio-Ruiz B, Galbraith L, et al.
Chem Sci
. 2018 Dec;
9(37):7354-7361.
PMID: 30542538
The incorporation of transition metal catalysts to the bioorthogonal toolbox has opened the possibility of producing supra-stoichiometric amounts of xenobiotics in living systems in a non-enzymatic fashion. For medical use,...
8.
Kotschy A, Szlavik Z, Murray J, Davidson J, Maragno A, Le Toumelin-Braizat G, et al.
Nature
. 2016 Oct;
538(7626):477-482.
PMID: 27760111
Avoidance of apoptosis is critical for the development and sustained growth of tumours. The pro-survival protein myeloid cell leukemia 1 (MCL1) is overexpressed in many cancers, but the development of...
9.
Schug Z, Frezza C, Galbraith L, Gottlieb E
Acta Oncol
. 2012 Jan;
51(3):301-10.
PMID: 22283492
Background: Lipids are best known for their fundamental role in forming biological membranes and as intracellular signalling molecules. Interactions between proteins and lipids are central to nearly every cellular process...
10.
Kemppainen E, Fernandez-Ayala D, Galbraith L, ODell K, Jacobs H
Mitochondrion
. 2009 Jul;
9(5):353-63.
PMID: 19616644
A mutation in the Drosophila gene technical knockout (tko(25t)), encoding mitoribosomal protein S12, phenocopies human mitochondrial disease. We isolated three spontaneous X-dominant suppressors of tko(25t) (designated Weeble), exhibiting almost wild-type...