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Laura Alejandra Ariza Orellano

Explore the profile of Laura Alejandra Ariza Orellano including associated specialties, affiliations and a list of published articles. Areas
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Citations 56
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Recent Articles
1.
Aguilar E, Fernandes-Braga W, Santos E, Leocadio P, Capettini L, Orellano L, et al.
Mol Cell Biochem . 2023 Jul; 479(6):1335-1347. PMID: 37402020
Obesity is closely associated with non-alcoholic fatty liver disease (NAFLD), characterized by hepatic fat accumulation and hepatocyte injury. Preclinical studies have shown exacerbated weight gain associated with an obesogenic gluten-containing...
2.
Scheuermann K, Viana C, Dos Reis D, de Lazari M, Orellano L, Machado C, et al.
IUBMB Life . 2023 Apr; 75(9):732-742. PMID: 37086464
Beyond its actions on the nervous system, amitriptyline (AM) has been shown to lower inflammatory, angiogenic, and fibrogenic markers in a few pathological conditions in human and in experimental animal...
3.
de Lazari M, Viana C, Pereira L, Orellano L, Ulrich H, Andrade S, et al.
Exp Physiol . 2022 Dec; 108(1):146-157. PMID: 36459573
New Findings: What is the central question of this study? Peritoneal injury can result in a persistent fibroproliferative process in the abdominal cavity, causing pain and loss of function of...
4.
Navia-Pelaez J, Dias M, Orellano L, Campos G, Alvarez-Leite J, Campos P, et al.
Eur J Pharmacol . 2022 Sep; 934:175255. PMID: 36088982
Background And Purpose: Amitriptyline (AM) is a classical and typical tricyclic antidepressant drug. Despite its well-known effects on the nervous system, it has been described to work as a TLR4...
5.
Viana C, Orellano L, Machado C, Almeida C, de Lazari M, Campos P, et al.
Microvasc Res . 2021 Nov; 139:104277. PMID: 34752815
Implantation of biomedical/synthetic devices to replace and/or repair biological tissues very often induces an adverse healing response (scarce angiogenesis, excessive collagen deposition) which is detrimental to implant functionality and integration...
6.
Pedretti S, Rena C, Orellano L, Lazari M, Campos P, Nunes T
Acta Cir Bras . 2020 Dec; 35(11):e301105. PMID: 33331455
Purpose: To assess the action of pentoxifylline, administered by subcutaneous route, on skin flap tissue repair in rats, and to verify the histological aspects and biomarkers. Methods: Thirty-two male Wistar...
7.
Scheuermann K, Orellano L, Viana C, Machado C, Lazari M, Capettini L, et al.
Inflammation . 2020 Oct; 44(2):580-591. PMID: 33034827
Recent data has signaled that in addition to its therapeutic indications as antidepressant and analgesic, amitriptyline (AM) exerts anti-inflammatory effects in humans and experimental animal models of acute inflammation. We...
8.
Orellano L, de Almeida S, Pereira L, Machado C, Viana C, Andrade S, et al.
Microvasc Res . 2020 May; 131:104014. PMID: 32450153
The damaging effects of obesity extend to multiple pre-existing tissue/organs. However, the influence of this condition on key components (inflammation and angiogenesis) of fibrovascular connective proliferating tissue, essential in repair...
9.
de Lazari M, Pereira L, Orellano L, Scheuermann K, Machado C, Vasconcelos A, et al.
Inflammation . 2020 Mar; 43(4):1259-1268. PMID: 32125592
Sodium butyrate (NaBu), a histone deacetylase inhibitor, has shown to exert beneficial actions attenuating inflammation in a number of intestinal and extra-intestinal diseases. However, the effects of NaBu on persistent...
10.
Viana C, Orellano L, Pereira L, de Almeida S, Couto L, de Lazari M, et al.
Inflammation . 2018 Aug; 41(6):2041-2051. PMID: 30069663
IL-33/ST2 axis has been shown to exert both pro- and anti- effects in wound healing and tumor development. To further understand the role of this cytokine complex, we characterized comparatively...