Lars Wieslander
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Explore the profile of Lars Wieslander including associated specialties, affiliations and a list of published articles.
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29
Citations
352
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Recent Articles
11.
Segerstolpe A, Granneman S, Bjork P, de Lima Alves F, Rappsilber J, Andersson C, et al.
Nucleic Acids Res
. 2012 Nov;
41(2):1178-90.
PMID: 23193268
Ribosomal subunit biogenesis in eukaryotes is a complex multistep process. Mrd1 is an essential and conserved small (40S) ribosomal subunit synthesis factor that is required for early cleavages in the...
12.
Kallberg Y, Segerstolpe A, Lackmann F, Persson B, Wieslander L
PLoS One
. 2012 Sep;
7(9):e43786.
PMID: 22984444
Ribosome biogenesis in eukaryotes requires coordinated folding and assembly of a pre-rRNA into sequential pre-rRNA-protein complexes in which chemical modifications and RNA cleavages occur. These processes require many small nucleolar...
13.
Bjork P, Wieslander L
Chromosoma
. 2010 Nov;
120(1):23-38.
PMID: 21079985
Nucleocytoplasmic export and biogenesis of mRNPs are closely coupled. At the gene, concomitant with synthesis of the pre-mRNA, the transcription machinery, hnRNP proteins, processing, quality control and export machineries cooperate...
14.
Kylberg K, Bjork P, Fomproix N, Ivarsson B, Wieslander L, Daneholt B
Exp Cell Res
. 2009 Oct;
316(6):1028-38.
PMID: 19853599
We have studied the nucleocytoplasmic transport of a specific messenger RNP (mRNP) particle, named Balbiani ring (BR) granule, and ribosomal RNP (rRNP) particles in the salivary glands of the dipteran...
15.
Lundkvist P, Jupiter S, Segerstolpe A, Osheim Y, Beyer A, Wieslander L
Mol Cell Biol
. 2009 Aug;
29(21):5763-74.
PMID: 19704003
In eukaryotes, ribosomes are made from precursor rRNA (pre-rRNA) and ribosomal proteins in a maturation process that requires a large number of snoRNPs and processing factors. A fundamental problem is...
16.
Bjork P, Jin S, Zhao J, Singh O, Persson J, Hellman U, et al.
J Cell Biol
. 2009 Feb;
184(4):555-68.
PMID: 19221196
Serine/arginine-rich (SR) proteins are required for messenger RNA (mRNA) processing, export, surveillance, and translation. We show that in Chironomus tentans, nascent transcripts associate with multiple types of SR proteins in...
17.
Bjork P, Wieslander L
Methods Mol Biol
. 2008 Oct;
464:29-54.
PMID: 18951178
Gene expression in eukaryotic cells is a multi-step process. Many of the steps are both co-ordinated and quality controlled. For example, transcription is closely coupled to pre-messenger RNA (mRNA)-protein assembly,...
18.
Segerstolpe A, Lundkvist P, Osheim Y, Beyer A, Wieslander L
Nucleic Acids Res
. 2008 Jul;
36(13):4364-80.
PMID: 18586827
In Saccharomyces cerevisiae, synthesis of the small ribosomal subunit requires assembly of the 35S pre-rRNA into a 90S preribosomal complex. SnoRNAs, including U3 snoRNA, and many trans-acting proteins are required...
19.
Singh O, Visa N, Wieslander L, Daneholt B
Chromosoma
. 2006 Jul;
115(6):449-58.
PMID: 16858590
The members of the serine-arginine (SR) family of proteins play multiple roles in posttranscriptional gene expression. Initially considered as essential splicing factors confined to the nucleus and regulating constitutive and...
20.
Bjork P, Wetterberg-Strandh I, Bauren G, Wieslander L
Mol Biol Cell
. 2005 Oct;
17(1):32-42.
PMID: 16236800
Chironomus tentans-repressor splicing factor (Ct-RSF) represses the activation of splicing by SR proteins in vitro. Ct-RSF colocalizes with the Ser-Arg-rich (SR) protein hrp45 in interchromatin granule clusters and coimmunoprecipitates with...