Lars Rose
Overview
Explore the profile of Lars Rose including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
809
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Recent Articles
1.
Wiehr S, von Ahsen O, Rose L, Mueller A, Mannheim J, Honndorf V, et al.
Mol Imaging Biol
. 2012 Aug;
15(2):203-11.
PMID: 22864665
Purpose: Here, we describe the efficacy of the novel small molecule c-Met inhibitor BAY 853474 in reducing tumor growth in the Hs746T gastric cancer xenograft model and tested the suitability...
2.
Gorges T, Tinhofer I, Drosch M, Rose L, Zollner T, Krahn T, et al.
BMC Cancer
. 2012 May;
12:178.
PMID: 22591372
Background: Circulating tumour cells (CTCs) have shown prognostic relevance in metastatic breast, prostate, colon and pancreatic cancer. For further development of CTCs as a biomarker, we compared the performance of...
3.
Rudolph M, Docke W, Muller A, Menning A, Rose L, Zollner T, et al.
PLoS One
. 2012 Mar;
7(3):e32922.
PMID: 22412950
The complex tissue remodeling process of menstruation is experienced by humans and some primates, whereas most placental mammals, including mice, go through an estrous cycle. How menstruation and the underlying...
4.
Rose L, Schneider C, Stock C, Zollner T, Docke W
Exp Dermatol
. 2011 Dec;
21(1):25-31.
PMID: 22151387
Despite recent developments, there is a high medical need for new treatment options for chronic inflammatory dermatoses like allergic contact dermatitis (ACD) and psoriasis. Particularly, more predictive skin inflammation models...
5.
Kerzerho J, Wunsch D, Szely N, Meyer H, Lurz L, Rose L, et al.
J Immunol
. 2011 Nov;
188(1):470-6.
PMID: 22105997
Respiratory exposure to allergen induces T cell tolerance and protection against the development of airway hyperactivity in animal models of asthma. Whereas systemic administration of dexamethasone during the delivery of...
6.
Schoepe S, Vonk R, Schacke H, Zollner T, Asadullah K, Rose L
Exp Dermatol
. 2011 Aug;
20(10):853-5.
PMID: 21824195
Glucocorticoids (GCs) belong to the most widely used anti-inflammatory drugs at all. However, their topical use is limited by their side effect potential, with skin atrophy being the most prominent...
7.
von Bonin A, Rausch A, Mengel A, Hitchcock M, Kruger M, von Ahsen O, et al.
Exp Dermatol
. 2010 Dec;
20(1):41-7.
PMID: 21158938
T-cell-mediated processes play an essential role in the pathogenesis of several inflammatory skin diseases such as atopic dermatitis, allergic contact dermatitis and psoriasis. The aim of this study was to...
8.
Schottelius A, Zugel U, Docke W, Zollner T, Rose L, Mengel A, et al.
J Invest Dermatol
. 2009 Aug;
130(2):481-91.
PMID: 19657354
Mitogen-activated protein kinase-activated protein kinase 2 (MK2) is a downstream molecule of p38, involved in the production of TNF-alpha, a key cytokine, and an established drug target for many inflammatory...
9.
Schneider C, Docke W, Zollner T, Rose L
J Invest Dermatol
. 2008 Oct;
129(4):899-907.
PMID: 18830270
Due to the steadily increasing incidence of atopic dermatitis (AD), especially in children, there is a high medical need for new therapies and improved animal models. In mice, trimellitic anhydride...
10.
Mirshahpanah P, Docke W, Merbold U, Asadullah K, Rose L, Schacke H, et al.
Exp Dermatol
. 2007 Aug;
16(9):753-61.
PMID: 17697148
Although introduced more than 50 years ago, topical glucocorticoids are still the first line therapy for many inflammatory skin disorders such as atopic eczema, contact dermatitis and many others. Recently,...