Lars Ronn Olsen
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Explore the profile of Lars Ronn Olsen including associated specialties, affiliations and a list of published articles.
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45
Citations
716
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Recent Articles
11.
Dam S, Olsen L, Vitting-Seerup K
BMC Biol
. 2023 Oct;
21(1):220.
PMID: 37858135
Background: Through alternative splicing, most human genes produce multiple isoforms in a cell-, tissue-, and disease-specific manner. Numerous studies show that alternative splicing is essential for development, diseases, and their...
12.
Parry E, Lemvigh C, Deng S, Dangle N, Ruthen N, Knisbacher B, et al.
Cancer Cell
. 2023 Sep;
41(10):1803-1816.e8.
PMID: 37738974
Unlike many other hematologic malignancies, Richter syndrome (RS), an aggressive B cell lymphoma originating from indolent chronic lymphocytic leukemia, is responsive to PD-1 blockade. To discover the determinants of response,...
13.
Eickhardt-Dalboge C, Ingham A, Nielsen H, Fuursted K, Stensvold C, Andersen L, et al.
Microbiol Spectr
. 2023 Sep;
:e0066223.
PMID: 37695126
Essential thrombocythemia (ET) is part of the Philadelphia chromosome-negative myeloproliferative neoplasms. It is characterized by an increased risk of thromboembolic events and also to a certain degree hypermetabolic symptoms. The...
14.
Shinde P, Soldevila F, Reyna J, Aoki M, Rasmussen M, Willemsen L, et al.
bioRxiv
. 2023 Sep;
PMID: 37693565
Computational models that predict an individual's response to a vaccine offer the potential for mechanistic insights and personalized vaccination strategies. These models are increasingly derived from systems vaccinology studies that...
15.
Hermann F, Kjaergaard M, Tian C, Tiemann U, Jackson A, Olsen L, et al.
Cell Stem Cell
. 2022 Dec;
30(1):38-51.e8.
PMID: 36563694
MODY3 is a monogenic hereditary form of diabetes caused by mutations in the transcription factor HNF1A. The patients progressively develop hyperglycemia due to perturbed insulin secretion, but the pathogenesis is...
16.
Eickhardt-Dalboge C, Ingham A, Andersen L, Nielsen H, Fuursted K, Stensvold C, et al.
Blood Adv
. 2022 Oct;
7(13):3326-3337.
PMID: 36260736
Chronic inflammation is believed to play an important role in the development and disease progression of polycythemia vera (PV). Because an association between gut microbiota, hematopoiesis, and inflammation is well...
17.
Lecoq I, Kopp K, Chapellier M, Mantas P, Martinenaite E, Perez-Penco M, et al.
Oncoimmunology
. 2022 Sep;
11(1):2115655.
PMID: 36052217
CCL22 is a macrophage-derived immunosuppressive chemokine that recruits regulatory T cells through the CCL22:CCR4 axis. CCL22 was shown to play a key role in suppressing anti-cancer immune responses in different...
18.
Barnkob M, Vitting-Seerup K, Olsen L
Immunother Adv
. 2022 Aug;
2(1):ltac009.
PMID: 35919495
The development of novel chimeric antigen receptor (CAR) cell therapies is rapidly growing, with 299 new agents being reported and 109 new clinical trials initiated so far this year. One...
19.
Pedersen C, Dam S, Barnkob M, Leipold M, Purroy N, Rassenti L, et al.
Nat Commun
. 2022 Apr;
13(1):1698.
PMID: 35361793
Combining single-cell cytometry datasets increases the analytical flexibility and the statistical power of data analyses. However, in many cases the full potential of co-analyses is not reached due to technical...
20.
Modvig S, Wernersson R, Obro N, Olsen L, Christensen C, Rosthoj S, et al.
Mol Oncol
. 2022 Mar;
16(10):2015-2030.
PMID: 35271751
Minimal residual disease (MRD) constitutes the most important prognostic factor in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Flow cytometry is widely used in MRD assessment, yet little is known regarding...