Lars Maegdefessel
Overview
Explore the profile of Lars Maegdefessel including associated specialties, affiliations and a list of published articles.
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Articles
176
Citations
4960
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Recent Articles
31.
Hardtner C, Kumar A, Ehlert C, Vico T, Starz C, von Ehr A, et al.
Atherosclerosis
. 2023 Mar;
371:1-13.
PMID: 36940535
Background And Aims: Atherosclerosis is a systemic and chronic inflammatory disease propagated by monocytes and macrophages. Yet, our knowledge on how transcriptome of these cells evolves in time and space...
32.
Zschapitz D, Bohmann B, Lutz B, Eckstein H, Reeps C, Maegdefessel L, et al.
JVS Vasc Sci
. 2023 Feb;
4:100093.
PMID: 36756656
Objective: The indication for abdominal aortic aneurysm (AAA) repair is based on a diameter threshold. However, mechanical properties, such as peak wall stress (PWS) and peak wall rupture index (PWRI),...
33.
Zhang W, Zhao J, Deng L, Ishimwe N, Pauli J, Wu W, et al.
bioRxiv
. 2023 Jan;
PMID: 36711681
Background: Activation of vascular smooth muscle cells (VSMCs) inflammation is vital to initiate vascular disease. However, the role of human-specific long noncoding RNAs (lncRNAs) in VSMC inflammation is poorly understood....
34.
Ferraro B, Giustetto P, Schengel O, Weckbach L, Maegdefessel L, Soehnlein O
Thromb Haemost
. 2023 Jan;
123(5):545-554.
PMID: 36596447
Background And Aim: The ability to recognize and monitor atherosclerotic lesion development using noninvasive imaging is crucial in preventive cardiology. The aim of the present study was to establish a...
35.
Cynn E, Li D, OReilly M, Wang Y, Bashore A, Jha A, et al.
Arterioscler Thromb Vasc Biol
. 2022 Dec;
43(2):286-299.
PMID: 36546321
Background: Long noncoding RNAs (lncRNAs) have emerged as novel regulators of macrophage biology and inflammatory cardiovascular diseases. However, studies focused on lncRNAs in human macrophage subtypes, particularly human lncRNAs that...
36.
Guillamat-Prats R, Hering D, Derle A, Rami M, Hardtner C, Santovito D, et al.
Nat Cardiovasc Res
. 2022 Dec;
1:1056-1071.
PMID: 36523570
Dissecting the pathways regulating the adaptive immune response in atherosclerosis is of particular therapeutic interest. Here we report that the lipid G-protein coupled receptor GPR55 is highly expressed by splenic...
37.
Reutersberg B, Metschl S, Salvermoser M, Eckstein H, Knappich C, Maegdefessel L, et al.
Vasa
. 2022 Dec;
52(2):124-132.
PMID: 36519232
Abdominal aortic aneurysm (AAA) rupture is still associated with a mortality rate of 80-90%. Imaging techniques or molecular fingerprinting for patient-specific risk stratification to identify pending rupture are still lacking....
38.
Fasolo F, Paloschi V, Maegdefessel L
Atherosclerosis
. 2022 Dec;
374:34-43.
PMID: 36513554
Despite extraordinary advances in the comprehension of the pathophysiology of atherosclerosis and the employment of very effective treatments, cardiovascular diseases are still a major cause of mortality and represent a...
39.
Lim C, Pratama M, Rivera C, Silvestro M, Tsao P, Maegdefessel L, et al.
Sci Rep
. 2022 Dec;
12(1):20990.
PMID: 36470918
Abdominal aortic aneurysms (AAA) is a multifactorial complex disease with life-threatening consequences. While Genome-wide association studies (GWAS) have revealed several single nucleotide polymorphisms (SNPs) located in the genome of individuals...
40.
Mulorz J, Spin J, Mulorz P, Wagenhauser M, Deng A, Mattern K, et al.
Cardiovasc Res
. 2022 Nov;
119(3):867-878.
PMID: 36413508
Aims: Abdominal aortic aneurysm (AAA) is a common cardiovascular disease with a strong correlation to smoking, although underlying mechanisms have been minimally explored. Electronic cigarettes (e-cigs) have gained recent broad...