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Lars Goebel

Explore the profile of Lars Goebel including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 261
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Recent Articles
1.
Peifer C, Olah T, Venkatesan J, Goebel L, Orth P, Schmitt G, et al.
Am J Sports Med . 2024 Mar; 52(5):1336-1349. PMID: 38482805
Background: Restoration of osteochondral defects is critical, because osteoarthritis (OA) can arise. Hypothesis: Overexpression of insulin-like growth factor 1 (IGF-1) via recombinant adeno-associated viral (rAAV) vectors (rAAV-IGF-1) would improve osteochondral...
2.
Winter P, Fritsch E, Tschernig T, Goebel L, Wolf M, Muller M, et al.
Medicina (Kaunas) . 2023 Sep; 59(9). PMID: 37763727
: Revision hip arthroplasty presents a surgical challenge, necessitating meticulous preoperative planning to avert complications like periprosthetic fractures and aseptic loosening. Historically, assessment of the accuracy of three-dimensional (3D) versus...
3.
Gao L, Beninatto R, Olah T, Goebel L, Tao K, Roels R, et al.
Adv Healthc Mater . 2023 Aug; 12(26):e2300931. PMID: 37567219
Articular cartilage defects represent an unsolved clinical challenge. Photopolymerizable hydrogels are attractive candidates supporting repair. This study investigates the short-term safety and efficacy of two novel hyaluronic acid (HA)-triethylene glycol...
4.
Wolf M, Goebel L, Winter P, Landgraeber S, Orth P
Front Surg . 2023 Jun; 10:1187223. PMID: 37377669
Introduction: Arthroplasty is the final treatment option for maintaining mobility and quality of life in many primary degenerative and (post-) traumatic joint diseases. Identification of research output and potential deficits...
5.
Maihofer J, Madry H, Rey-Rico A, Venkatesan J, Goebel L, Schmitt G, et al.
Adv Mater . 2021 Mar; 33(16):e2008451. PMID: 33734514
The regeneration of focal articular cartilage defects is complicated by the reduced quality of the repair tissue and the potential development of perifocal osteoarthritis (OA). Biomaterial-guided gene therapy may enhance...
6.
Goebel L, Kohn D, Grun U
Dtsch Arztebl Int . 2020 Jan; 116(50):857. PMID: 31931954
No abstract available.
7.
Goebel L, Schneider G, Bohle R, Veith C, Orth P
Lancet . 2019 Dec; 394(10215):2197. PMID: 31839190
No abstract available.
8.
Madry H, Gao L, Rey-Rico A, Venkatesan J, Muller-Brandt K, Cai X, et al.
Adv Mater . 2019 Nov; 32(2):e1906508. PMID: 31763733
Advanced biomaterial-guided delivery of gene vectors is an emerging and highly attractive therapeutic solution for targeted articular cartilage repair, allowing for a controlled and minimally invasive delivery of gene vectors...
9.
Cucchiarini M, Asen A, Goebel L, Venkatesan J, Schmitt G, Zurakowski D, et al.
Am J Sports Med . 2018 May; 46(8):1987-1996. PMID: 29792508
Background: Application of the chondrogenic transforming growth factor beta (TGF-β) is an attractive approach to enhance the intrinsic biological activities in damaged articular cartilage, especially when using direct gene transfer...
10.
Asen A, Goebel L, Rey-Rico A, Sohier J, Zurakowski D, Cucchiarini M, et al.
FASEB J . 2018 Apr; 32(10):5298-5311. PMID: 29688810
The continuous presence of TGF-β is critically important to induce effective chondrogenesis. To investigate chondrogenesis in a cartilage defect, we tested the hypothesis that the implantation of TGF-β1-releasing scaffolds improves...