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Lars F Olsen

Explore the profile of Lars F Olsen including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 169
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Recent Articles
11.
Thoke H, Bagatolli L, Olsen L
Integr Biol (Camb) . 2018 Sep; 10(10):587-597. PMID: 30176029
Water is involved in all aspects of biological activity, both as a solvent and as a reactant. It is hypothesized that intracellular water is in a highly structured state due...
12.
Thoke H, Olsen L, Duelund L, Stock R, Heimburg T, Bagatolli L
J Biol Phys . 2018 May; 44(3):419-431. PMID: 29796745
We measured temporal oscillations in thermodynamic variables such as temperature, heat flux, and cellular volume in suspensions of non-dividing yeast cells which exhibit temporal glycolytic oscillations. Oscillations in these variables...
13.
Thoke H, Thorsteinsson S, Stock R, Bagatolli L, Olsen L
Sci Rep . 2017 Nov; 7(1):16250. PMID: 29176686
We explored the dynamic coupling of intracellular water with metabolism in yeast cells. Using the polarity-sensitive probe 6-acetyl-2-dimethylaminonaphthalene (ACDAN), we show that glycolytic oscillations in the yeast S. cerevisiae BY4743...
14.
Thoke H, Tobiesen A, Brewer J, Hansen P, Stock R, Olsen L, et al.
PLoS One . 2015 Feb; 10(2):e0117308. PMID: 25705902
We detected very strong coupling between the oscillating concentration of ATP and the dynamics of intracellular water during glycolysis in Saccharomyces cerevisiae. Our results indicate that: i) dipolar relaxation of...
15.
Schroder T, Ozalp V, Lunding A, Jernshoj K, Olsen L
FEBS J . 2013 Sep; 280(23):6033-44. PMID: 24028352
We have studied oscillating glycolysis in the strain BY4743 and isogenic strains with deletions of genes encoding enzymes in glycolysis, mitochondrial electron transport and ATP synthesis. We found that deletion...
16.
Ozalp V, Zeydanli U, Lunding A, Kavruk M, Oz M, Eyidogan F, et al.
Analyst . 2013 Jun; 138(15):4255-9. PMID: 23730687
In this study, combining the nanoparticle embedded sensors with lateral flow assays, a novel strategy for ensuring the quality of signalling in lateral flow assays (LFAs) was developed. A LFA...
17.
Ozalp V, Nielsen L, Olsen L
Chembiochem . 2010 Nov; 11(18):2538-41. PMID: 21086483
No abstract available.
18.
Ozalp V, Pedersen T, Nielsen L, Olsen L
J Biol Chem . 2010 Oct; 285(48):37579-88. PMID: 20880841
Adenosine 5'-triphosphate is a universal molecule in all living cells, where it functions in bioenergetics and cell signaling. To understand how the concentration of ATP is regulated by cell metabolism...
19.
Nielsen L, Olsen L, Ozalp V
ACS Nano . 2010 Aug; 4(8):4361-70. PMID: 20731422
We describe a new type of aptamer-based optical nanosensor which uses the embedding of target responsive oligonucleotides in porous polyacrylamide nanoparticles to eliminate nuclease instability. The latter is a common...
20.
Poulsen A, Scharff-Poulsen A, Olsen L
Anal Biochem . 2007 May; 366(1):29-36. PMID: 17498639
We have synthesized and characterized new nanometer-sized polyacrylamide particles containing horseradish peroxidase and fluorescent dyes. Proteins and dyes are encapsulated by radical polymerization in inverse microemulsion. The activity of the...