Lars E P Dietrich
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Explore the profile of Lars E P Dietrich including associated specialties, affiliations and a list of published articles.
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72
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2848
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Recent Articles
21.
Evans C, Kempes C, Price-Whelan A, Dietrich L
Trends Microbiol
. 2020 Aug;
28(9):732-743.
PMID: 32781027
Cells in assemblages differentiate and perform distinct roles. Though many pathways of differentiation are understood at the molecular level in multicellular eukaryotes, the elucidation of similar processes in bacterial assemblages...
22.
Shi L, Liu X, Shi L, Stinson H, Rowlette J, Kahl L, et al.
Nat Methods
. 2020 Jul;
17(8):844-851.
PMID: 32601425
Understanding metabolism is indispensable in unraveling the mechanistic basis of many physiological and pathological processes. However, in situ metabolic imaging tools are still lacking. Here we introduce a framework for...
23.
Kahl L, Price-Whelan A, Dietrich L
J Bacteriol
. 2020 May;
202(14).
PMID: 32366589
Light is known to trigger regulatory responses in diverse organisms, including slime molds, animals, plants, and phototrophic bacteria. However, light-dependent processes in nonphototrophic bacteria, and those of pathogens in particular,...
24.
Luu G, Condren A, Kahl L, Dietrich L, Sanchez L
J Am Soc Mass Spectrom
. 2020 Apr;
31(6):1313-1320.
PMID: 32329613
Imaging mass spectrometry (IMS) has proven to be a useful tool when investigating the spatial distributions of metabolites and proteins in a biological system. One of the biggest advantages of...
25.
Condren A, Kahl L, Boelter G, Kritikos G, Banzhaf M, Dietrich L, et al.
ACS Infect Dis
. 2019 Dec;
6(4):603-612.
PMID: 31851822
Biofilm inhibition by exogenous molecules has been an attractive strategy for the development of novel therapeutics. We investigated the biofilm inhibitor taurolithocholic acid (TLCA) and its effects on the specialized...
26.
Jo J, Price-Whelan A, Cornell W, Dietrich L
J Bacteriol
. 2019 Nov;
202(4).
PMID: 31767778
Extracellular electron transfer (EET), the reduction of compounds that shuttle electrons to distal oxidants, can support bacterial survival when preferred oxidants are not directly accessible. EET has been shown to...
27.
Schiessl K, Hu F, Jo J, Nazia S, Wang B, Price-Whelan A, et al.
Nat Commun
. 2019 Feb;
10(1):762.
PMID: 30770834
Antibiotic efficacy can be antagonized by bioactive metabolites and other drugs present at infection sites. Pseudomonas aeruginosa, a common cause of biofilm-based infections, releases metabolites called phenazines that accept electrons...
28.
Lin Y, Cornell W, Jo J, Price-Whelan A, Dietrich L
mBio
. 2018 Sep;
9(5).
PMID: 30206167
is the most common cause of chronic, biofilm-based lung infections in patients with cystic fibrosis (CF). Sputum from patients with CF has been shown to contain oxic and hypoxic subzones...
29.
Cornell W, Morgan C, Koyama L, Sakhtah H, Mansfield J, Dietrich L
J Vis Exp
. 2018 Apr;
(133).
PMID: 29630036
Sectioning via paraffin embedding is a broadly established technique in eukaryotic systems. Here we provide a method for the fixation, embedding, and sectioning of intact microbial colony biofilms using perfused...
30.
Sporer A, Beierschmitt C, Bendebury A, Zink K, Price-Whelan A, Buzzeo M, et al.
Microbiology (Reading)
. 2018 Apr;
164(5):790-800.
PMID: 29629858
The activities of critical metabolic and regulatory proteins can be altered by exposure to natural or synthetic redox-cycling compounds. Many bacteria, therefore, possess mechanisms to transport or transform these small...