Lars Bruce
Overview
Explore the profile of Lars Bruce including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
33
Followers
0
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Recent Articles
1.
Srinivasan V, Homer V, Barton D, Clutterbuck-James A, Jenkins S, Potter C, et al.
PLoS One
. 2024 Jul;
19(7):e0291285.
PMID: 38990927
Background: Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig´s disease, is a rare neurological condition and is the most common motor neurone disease. It is a fatal disease with...
2.
Logan A, Belli A, Di Pietro V, Tavazzi B, Lazzarino G, Mangione R, et al.
Front Pharmacol
. 2022 Sep;
13:983853.
PMID: 36110516
Acute and chronic neurodegenerative diseases represent an immense socioeconomic burden that drives the need for new disease modifying drugs. Common pathogenic mechanisms in these diseases are evident, suggesting that a...
3.
Lazzarino G, Di Pietro V, Rinaudo M, Nagy Z, Barnes N, Bruce L, et al.
Int J Mol Sci
. 2022 Aug;
23(15).
PMID: 35955592
In a previous study, we found that administration of ILB, a new low molecular weight dextran sulphate, significantly improved mitochondrial functions and energy metabolism, as well as decreased oxidative/nitrosative stress,...
4.
Logan A, Nagy Z, Barnes N, Belli A, Di Pietro V, Tavazzi B, et al.
PLoS One
. 2022 May;
17(5):e0267183.
PMID: 35613082
Introduction: Amyotrophic lateral sclerosis (ALS) is an invariably lethal progressive disease, causing degeneration of neurons and muscle. No current treatment halts or reverses disease advance. This single arm, open label,...
5.
Lazzarino G, Mangione R, Belli A, Di Pietro V, Nagy Z, Barnes N, et al.
J Pers Med
. 2021 Aug;
11(8).
PMID: 34442438
Oxidative/nitrosative stress and mitochondrial dysfunction is a hallmark of amyotrophic lateral sclerosis (ALS), an invariably fatal progressive neurodegenerative disease. Here, as an exploratory arm of a phase II clinical trial...
6.
Hill L, Botfield H, Begum G, Qureshi O, Vigneswara V, Masood I, et al.
NPJ Regen Med
. 2021 Jan;
6(1):3.
PMID: 33414477
Fibrotic disease is a major cause of mortality worldwide, with fibrosis arising from prolonged inflammation and aberrant extracellular matrix dynamics. Compromised cellular and tissue repair processes following injury, infection, metabolic...
7.
Lazzarino G, Amorini A, Barnes N, Bruce L, Mordente A, Lazzarino G, et al.
Antioxidants (Basel)
. 2020 Sep;
9(9).
PMID: 32927770
Traumatic brain injury (TBI) is the leading cause of death and disability in people less than 40 years of age in Western countries. Currently, there are no satisfying pharmacological treatments...
8.
Alffram P, Bruce L, Bjursten L, Urban R, Andersson G
Ups J Med Sci
. 2007 Jun;
112(2):183-9.
PMID: 17578818
This study describes a new method for the fixation of titanium hip stem prostheses based on interdigitation of irregularly shaped porous titanium granules onto bone tissue. The granules were distributed...