Lars B Nilsson
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Explore the profile of Lars B Nilsson including associated specialties, affiliations and a list of published articles.
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12
Citations
91
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Recent Articles
1.
Nilsson L
Bioanalysis
. 2013 Dec;
5(24):3033-50.
PMID: 24320129
Knowledge regarding unbound concentrations is of vital importance when exploring the PK and PD of a drug. The accurate and reproducible determination of plasma protein binding and unbound concentrations for...
2.
Ekerot P, Ferguson D, Glamsta E, Nilsson L, Andersson H, Rosqvist S, et al.
Pharm Res
. 2013 Apr;
30(6):1513-24.
PMID: 23568527
Purpose: To develop a systems pharmacology model based on hormone physiology and pharmacokinetic-pharmacodynamic concepts describing the impact of thyroperoxidase (TPO) inhibition on thyroid hormone homeostasis in the dog and to...
3.
Nilsson L, Ahnoff M, Jonsson O
Bioanalysis
. 2013 Mar;
5(6):731-8.
PMID: 23484790
Capillary microsampling (CMS) has recently been introduced as a response to the demands for more ethical use of laboratory animals according to the 3R principles. In CMS, an exact volume...
4.
Jonsson O, Palma Villar R, Nilsson L, Eriksson M, Konigsson K
Bioanalysis
. 2012 Sep;
4(16):1989-98.
PMID: 22946915
Background: Capillary microsampling was recently introduced as a new technique for simplified collection and handling of small, exact volumes of liquid matrices. In this article, a bioanalytical method was developed...
5.
Olsson A, Liljeblad M, Nilsson L, Silvester S
Bioanalysis
. 2012 Aug;
4(14):1705-8.
PMID: 22877214
No abstract available.
6.
Nilsson L, Skansen P
Rapid Commun Mass Spectrom
. 2012 May;
26(12):1399-406.
PMID: 22592983
Rationale: The investigations in this article were triggered by two observations in the laboratory; for some liquid chromatography/tandem mass spectrometry (LC/MS/MS) systems it was possible to obtain linear calibration curves...
7.
Jonsson O, Palma Villar R, Nilsson L, Norsten-Hoog C, Brogren J, Eriksson M, et al.
Bioanalysis
. 2012 Mar;
4(6):661-74.
PMID: 22452257
Background: Capillary microsampling (CMS) is a new technique for simplified collection, handling and analysis of small, exact volumes of liquid matrices. CMS was compared with conventional large volume sampling, in...
8.
Ollerstam A, Visser S, Duker G, Forsberg T, Persson A, Nilsson L, et al.
J Pharmacol Toxicol Methods
. 2007 Aug;
56(2):131-44.
PMID: 17689270
Introduction: The aim of the present study was to compare sensitivity in detecting the drug-induced QT interval prolongation in three dog models: conscious telemetered at sinus rhythm and conscious and...
9.
Nilsson L, Eklund G
J Pharm Biomed Anal
. 2006 Nov;
43(3):1094-9.
PMID: 17084056
The possibility to rationalize and simplify bioanalysis, without compromising the analytical quality, by omitting the calibration curves was studied. Using mass spectrometry (MS) and a stable isotope labeled internal standard...
10.
Ollerstam A, Persson A, Visser S, Fredriksson J, Forsberg T, Nilsson L, et al.
J Pharmacol Toxicol Methods
. 2006 Apr;
55(1):35-48.
PMID: 16581270
Introduction: Drug-induced QT interval prolongation may lead to ventricular arrhythmias. The aim of the study was to optimize QT interval data processing to quantify drug-induced QT interval prolongation in the...