Larry Xi
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Explore the profile of Larry Xi including associated specialties, affiliations and a list of published articles.
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3
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16
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Recent Articles
1.
Leong P, Mihajlovic A, Bogdanovic N, Breberina L, Xi L
Sci Rep
. 2021 Sep;
11(1):18907.
PMID: 34556684
Single-cell sequencing provides a new level of granularity in studying the heterogeneous nature of cancer cells. For some cancers, this heterogeneity is the result of copy number changes of genes...
2.
Xi L, Leong P, Mihajlovic A
Bio Protoc
. 2021 Mar;
9(4):e3175.
PMID: 33654981
Single-cell DNA sequencing is a powerful tool to evaluate the state of heterogeneity of heterogeneous tissues like cancer in a quantitative manner that bulk sequencing can never achieve. DOP-PCR (Degenerate...
3.
Xi L, Belyaev A, Spurgeon S, Wang X, Gong H, Aboukhalil R, et al.
PLoS One
. 2017 Jul;
12(7):e0181163.
PMID: 28723968
A central challenge in sequencing single-cell genomes is the accurate determination of point mutations, phasing of these mutations, and identifying copy number variations with few assumptions. Ideally, this is accomplished...