Larissa Kotelevets
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Explore the profile of Larissa Kotelevets including associated specialties, affiliations and a list of published articles.
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Citations
525
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Recent Articles
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2.
Kotelevets L, Chastre E
Cancers (Basel)
. 2023 Feb;
15(4).
PMID: 36831450
Colorectal cancer (CRC) is a leading public health concern due to its incidence and high mortality rates, highlighting the requirement of an early diagnosis. Evaluation of circulating extracellular vesicles (EVs)...
3.
Kotelevets L, Chastre E
Cancers (Basel)
. 2021 Sep;
13(17).
PMID: 34503076
Scaffolding molecules exert a critical role in orchestrating cellular response through the spatiotemporal assembly of effector proteins as signalosomes. By increasing the efficiency and selectivity of intracellular signaling, these molecules...
4.
Kotelevets L, Chastre E
Cancers (Basel)
. 2020 Mar;
12(3).
PMID: 32178475
The small GTPase Rac1 has been implicated in a variety of dynamic cell biological processes, including cell proliferation, cell survival, cell-cell contacts, epithelial mesenchymal transition (EMT), cell motility, and invasiveness....
5.
Kotelevets L, Trifault B, Chastre E, Scott M
Cold Spring Harb Perspect Med
. 2020 Jan;
10(7).
PMID: 31932468
Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a tumor suppressor that is frequently down-modulated in human cancer. PTEN inhibits the phosphatidylinositol 3-phosphate kinase (PI3K)/AKT pathway through its...
6.
Kotelevets L, Scott M, Chastre E
Adv Exp Med Biol
. 2019 Jan;
1110:55-73.
PMID: 30623366
Phosphatase and tensin homolog (PTEN) is a tumour suppressor that represents one of the most common targets for genetic defect in human cancer. PTEN controls an array of physiopathological processes...
7.
Kotelevets L, Walker F, Mamadou G, Lehy T, Jordan P, Chastre E
Oncogene
. 2018 Jul;
37(46):6054-6068.
PMID: 29985482
We previously have identified the ectopic expression of Rac1b, an activated and novel splice variant of Rac1, in a subset of human colorectal adenocarcinomas, as well as in inflammatory bowel...
8.
Kotelevets L, Chastre E, Caron J, Mougin J, Bastian G, Pineau A, et al.
Cancer Res
. 2017 Apr;
77(11):2964-2975.
PMID: 28416486
Nanotechnology offers many possibilities to improve drug treatments, including with regard to drug pharmacology. The current study reports a simple approach to improve cisplatin efficacy in the treatment of colon...
9.
Foudi N, Ozen G, Amgoud Y, Louedec L, Choqueux C, Badi A, et al.
Eur J Pharmacol
. 2017 Apr;
804:31-37.
PMID: 28373136
Cyclooxygenase-2 (COX-2) induction in human internal mammary arteries (IMA) under inflammatory conditions has been associated with attenuated norepinephrine (NE)-induced vasoconstriction. This effect was associated with increased prostaglandin (PG) E and...
10.
Kotelevets L, Chastre E, Desmaele D, Couvreur P
Int J Pharm
. 2016 Nov;
514(1):24-40.
PMID: 27863668
Colorectal cancer is a wide-reaching health problem due to its incidence and to the high mortality rates. Adjuvant chemotherapies have considerably improved the prognosis and/or the overall survival of patients...