Larissa C da Rosa
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Explore the profile of Larissa C da Rosa including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
18
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Recent Articles
1.
da Rosa L, Scales H, Benson R, Brewer J, McInnes I, Garside P
Discov Immunol
. 2024 Apr;
3(1):kyad029.
PMID: 38567291
Abatacept, a co-stimulatory blocker comprising the extracellular portion of human CTLA-4 linked to the Fc region of IgG1, is approved for the treatment of rheumatoid arthritis. By impairing the interaction...
2.
da Rosa L, Scales H, Makhija S, Sutherland K, Benson R, Brewer J, et al.
Discov Immunol
. 2024 Apr;
1(1):kyac008.
PMID: 38566907
One of the earliest signs of dysregulation of the homeostatic process of fibrosis, associated with pathology in chronic conditions such as rheumatoid arthritis, is the overexpression of collagen type III...
3.
Boldison J, da Rosa L, Buckingham L, Davies J, Wen L, Wong F
Diabetologia
. 2019 Aug;
62(11):2052-2065.
PMID: 31444529
Aims/hypothesis: Autoreactive B cells escape immune tolerance and contribute to the pathogenesis of type 1 diabetes. While global B cell depletion is a successful therapy for autoimmune disease, the fate...
4.
da Rosa L, Boldison J, De Leenheer E, Davies J, Wen L, Wong F
Diabetologia
. 2018 Mar;
61(6):1397-1410.
PMID: 29594371
Aims/hypothesis: Type 1 diabetes is a T cell-mediated autoimmune disease characterised by the destruction of beta cells in the islets of Langerhans, resulting in deficient insulin production. B cell depletion...