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Paul Garside

Explore the profile of Paul Garside including associated specialties, affiliations and a list of published articles. Areas
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Articles 106
Citations 2137
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Recent Articles
1.
da Rosa L, Scales H, Benson R, Brewer J, McInnes I, Garside P
Discov Immunol . 2024 Apr; 3(1):kyad029. PMID: 38567291
Abatacept, a co-stimulatory blocker comprising the extracellular portion of human CTLA-4 linked to the Fc region of IgG1, is approved for the treatment of rheumatoid arthritis. By impairing the interaction...
2.
da Rosa L, Scales H, Makhija S, Sutherland K, Benson R, Brewer J, et al.
Discov Immunol . 2024 Apr; 1(1):kyac008. PMID: 38566907
One of the earliest signs of dysregulation of the homeostatic process of fibrosis, associated with pathology in chronic conditions such as rheumatoid arthritis, is the overexpression of collagen type III...
3.
Meehan G, Scales H, McInnes I, Brewer J, Garside P
Immunother Adv . 2022 Oct; 2(1):ltac020. PMID: 36268500
Currently, treatments for rheumatoid arthritis (RA) are focussed on management of disease symptoms rather than addressing the cause of disease, which could lead to remission and cure. Central to disease...
4.
Prendergast C, Benson R, Scales H, Bonilha C, Cole J, McInnes I, et al.
JCI Insight . 2022 Feb; 7(7). PMID: 35192549
Mechanisms governing entry and exit of immune cells into and out of inflamed joints remain poorly understood. We sought herein to identify the key molecular pathways regulating such migration. Using...
5.
Raponi A, Brewer J, Garside P, Laera D
Semin Immunol . 2022 Feb; 59:101596. PMID: 35148956
No abstract available.
6.
Raponi A, Brewer J, Garside P, Laera D
Semin Immunol . 2021 Dec; 56:101544. PMID: 34895823
Purified vaccine antigens offer important safety and reactogenicity advantages compared with live attenuated or whole killed virus and bacterial vaccines. However, they require the addition of adjuvants to induce the...
7.
Girard A, Cooper A, Mabbott S, Bradley B, Asiala S, Jamieson L, et al.
PLoS Pathog . 2021 Nov; 17(11):e1010060. PMID: 34780575
Human African Trypanosomiasis (HAT) has been responsible for several deadly epidemics throughout the 20th century, but a renewed commitment to disease control has significantly reduced new cases and motivated a...
8.
Alfituri O, Quintana J, MacLeod A, Garside P, Benson R, Brewer J, et al.
Front Immunol . 2021 Nov; 12:780758. PMID: 34777397
[This corrects the article DOI: 10.3389/fimmu.2020.01250.].
9.
Bedaj M, Bonilha C, McInnes I, Garside P, Benson R
Clin Exp Rheumatol . 2021 Sep; 40(7):1313-1323. PMID: 34494958
Objectives: Janus kinases (JAK) are key cell membrane orientated tyrosine kinases that regulate inflammatory responses by transducing signals received by cytokine receptors that directly influence the polarisation and function of...
10.
Meehan G, Thomas R, Al Khabouri S, Wehr P, Hilkens C, Wraith D, et al.
Ann Rheum Dis . 2021 Aug; 80(10):1268-1277. PMID: 34380700
Increasingly earlier identification of individuals at high risk of rheumatoid arthritis (RA) (eg, with autoantibodies and mild symptoms) improves the feasibility of preventing or curing disease. The use of antigen-specific...