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Lara Schneider

Explore the profile of Lara Schneider including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 332
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Recent Articles
1.
Schick M, Zhang L, Maurer S, Maurer H, Isaakaidis K, Schneider L, et al.
Nat Commun . 2022 Jan; 13(1):281. PMID: 35022408
SUMOylation is a post-translational modification of proteins that regulates these proteins' localization, turnover or function. Aberrant SUMOylation is frequently found in cancers but its origin remains elusive. Using a genome-wide...
2.
Gerstner N, Kehl T, Lenhof K, Eckhart L, Schneider L, Stockel D, et al.
Front Mol Biosci . 2021 Oct; 8:716544. PMID: 34604304
Experimental high-throughput techniques, like next-generation sequencing or microarrays, are nowadays routinely applied to create detailed molecular profiles of cells. In general, these platforms generate high-dimensional and noisy data sets. For...
3.
Konerding U, Redaelli M, Ackermann K, Altin S, Appelbaum S, Biallas B, et al.
Trials . 2021 Sep; 22(1):659. PMID: 34579783
Background: Type 2 diabetes mellitus (T2DM) and coronary heart disease (CHD) are two chronic diseases that cause a tremendous burden. To reduce this burden, several programmes for optimising the care...
4.
Lenhof K, Gerstner N, Kehl T, Eckhart L, Schneider L, Lenhof H
Bioinformatics . 2021 Aug; 37(21):3881-3888. PMID: 34352075
Motivation: A major goal of personalized medicine in oncology is the optimization of treatment strategies given measurements of the genetic and molecular profiles of cancer cells. To further our knowledge...
5.
Liu J, Wilcox S, Wingard E, Burgis J, Schneider L, Dahl A
Womens Health Rep (New Rochelle) . 2021 Mar; 1(1):556-565. PMID: 33786522
Pregnant women with elevated body mass index (BMI) are difficult to recruit into lifestyle studies. This article (1) summarized strategies to recruit pregnant women into a randomized trial, and (2)...
6.
Biederstadt A, Hassan Z, Schneeweis C, Schick M, Schneider L, Muckenhuber A, et al.
Gut . 2020 Feb; 69(8):1472-1482. PMID: 32001555
Objective: Pancreatic ductal adenocarcinoma (PDAC) still carries a dismal prognosis with an overall 5-year survival rate of 9%. Conventional combination chemotherapies are a clear advance in the treatment of PDAC;...
7.
Schneider L, Kehl T, Thedinga K, Grammes N, Backes C, Mohr C, et al.
Bioinformatics . 2019 May; 35(24):5171-5181. PMID: 31038669
Motivation: Breast cancer is the second leading cause of cancer death among women. Tumors, even of the same histopathological subtype, exhibit a high genotypic diversity that impedes therapy stratification and...
8.
Schneider L, Su L, Arab L, Bensen J, Farnan L, Fontham E, et al.
Ann Epidemiol . 2018 Oct; 29:16-22.e1. PMID: 30268488
Background: Several foods and nutrients have been linked to the development of prostate cancer, but the association between healthy dietary patterns and prostate cancer aggressiveness is less studied. The aim...
9.
Kehl T, Schneider L, Kattler K, Stockel D, Wegert J, Gerstner N, et al.
Int J Cancer . 2018 Aug; 144(6):1432-1443. PMID: 30155889
Wilms tumors are the most common type of pediatric kidney tumors. While the overall prognosis for patients is favorable, especially tumors that exhibit a blastemal subtype after preoperative chemotherapy have...
10.
Kehl T, Schneider L, Kattler K, Stockel D, Wegert J, Gerstner N, et al.
Bioinformatics . 2018 May; 34(20):3503-3510. PMID: 29741575
Motivation: Transcriptional regulators play a major role in most biological processes. Alterations in their activities are associated with a variety of diseases and in particular with tumor development and progression....