Lara J Kohler
Overview
Explore the profile of Lara J Kohler including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
430
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Recent Articles
1.
Trevino S, Klimko C, Reed M, Aponte-Cuadrado M, Hunter M, Shoe J, et al.
PLoS One
. 2018 Dec;
13(11):e0208277.
PMID: 30500862
Mouse models have been essential to generate supporting data for the research of infectious diseases. Burkholderia pseudomallei, the etiological agent of melioidosis, has been studied using mouse models to investigate...
2.
Kohler L, Roy C
Curr Opin Microbiol
. 2016 Dec;
35:36-41.
PMID: 27984783
Eukaryotic cells use autophagy to break down and recycle components such as aggregated proteins and damaged organelles. Research in the past decade, particularly using Salmonella enterica serovar Typhimurium as a...
3.
Kohler L, Reed S, Sarraf S, Arteaga D, Newton H, Roy C
mBio
. 2016 Sep;
7(5).
PMID: 27601576
No abstract available.
4.
Kohler L, Reed S, Sarraf S, Arteaga D, Newton H, Roy C
mBio
. 2016 Jul;
7(4).
PMID: 27435465
Unlabelled: Coxiella burnetii replicates in an acidified lysosome-derived vacuole. Biogenesis of the Coxiella-containing vacuole (CCV) requires bacterial effector proteins delivered into host cells by the Dot/Icm secretion system. Genetic and...
5.
Horenkamp F, Kauffman K, Kohler L, Sherwood R, Krueger K, Shteyn V, et al.
Dev Cell
. 2015 Sep;
34(5):569-76.
PMID: 26343456
Autophagy is a conserved membrane transport pathway used to destroy pathogenic microbes that access the cytosol of cells. The intracellular pathogen Legionella pneumophila interferes with autophagy by delivering an effector...
6.
Kohler L, Roy C
Microbes Infect
. 2015 Sep;
17(11-12):766-71.
PMID: 26327296
Coxiella burnetii utilizes a Type IV Secretion System (T4SS) to modify host endomembrane transport systems to form a unique lysosome-derived niche called the Coxiella-containing vacuole (CCV). Although the CCV has...
7.
Newton H, Kohler L, McDonough J, Temoche-Diaz M, Crabill E, Hartland E, et al.
PLoS Pathog
. 2014 Aug;
10(7):e1004286.
PMID: 25080348
Coxiella burnetii is an intracellular pathogen that replicates in a lysosome-derived vacuole. The molecular mechanisms used by this bacterium to create a pathogen-occupied vacuole remain largely unknown. Here, we conducted...
8.
Case C, Kohler L, Lima J, Strowig T, de Zoete M, Flavell R, et al.
Proc Natl Acad Sci U S A
. 2013 Jan;
110(5):1851-6.
PMID: 23307811
A flagellin-independent caspase-1 activation pathway that does not require NAIP5 or NRLC4 is induced by the intracellular pathogen Legionella pneumophila. Here we demonstrate that this pathway requires caspase-11. Treatment of...
9.
Kohler L, Carton Y, Mastore M, Nappi A
Arch Insect Biochem Physiol
. 2007 Sep;
66(2):64-75.
PMID: 17879234
In insects, eukaryotic endoparasites encounter a series of innate immune effector responses mediated in large part by circulating blood cells (hemocytes) that rapidly form multilayer capsules around foreign organisms. Critical...