Lara Ibrahim
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Explore the profile of Lara Ibrahim including associated specialties, affiliations and a list of published articles.
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13
Citations
98
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Recent Articles
1.
Buschmann E, Van Steenkiste G, Duytschaever M, Segers P, Ibrahim L, van Loon G, et al.
Sci Rep
. 2024 Oct;
14(1):22877.
PMID: 39358479
Radiofrequency ablation is a promising technique for arrhythmia treatment in horses. Due to the thicker myocardial wall and higher blood flow in horses, it is unknown if conventional radiofrequency settings...
2.
Vernemmen I, Van Steenkiste G, Buschmann E, Cornelis K, Schauvliege S, Ibrahim L, et al.
Equine Vet J
. 2024 Mar;
57(1):243-255.
PMID: 38522423
Background: Radiofrequency ablation has been successfully applied to treat right atrial arrhythmias in horses. Ablation of left-sided arrhythmias requires a retrograde transarterial approach which is complicated. In human medicine, the...
3.
Ibrahim L, Buschmann E, van Loon G, Cornillie P
Equine Vet J
. 2024 Feb;
57(1):256-264.
PMID: 38391272
Background: Three-dimensional electro-anatomical mapping, previously performed in horses with atrial arrhythmias, has demonstrated the medial region of the caudal vena cava (CaVC), 1-8 cm caudal to the fossa ovalis, as...
4.
Buschmann E, Van Steenkiste G, Duytschaever M, Boussy T, Vernemmen I, Ibrahim L, et al.
Equine Vet J
. 2023 Dec;
56(5):1068-1076.
PMID: 38151793
Background: Recently, treatment of equine atrial tachycardia by three-dimensional electro-anatomical mapping (3D EAM) and radiofrequency catheter ablation (RFCA) has been described. Myocardial sleeves in the caudal vena cava and pulmonary...
5.
Ibrahim L, Stanton C, Nutsch K, Nguyen T, Li-Ma C, Ko Y, et al.
Cell Chem Biol
. 2023 Aug;
30(10):1295-1302.e4.
PMID: 37619563
Cross talk between metabolism and stress-responsive signaling is essential for maintaining cellular homeostasis. This cross talk is often achieved through covalent modification of proteins by endogenous, reactive metabolites that regulate...
6.
Ibrahim L, Stanton C, Nutsch K, Nguyen T, Li-Ma C, Ko Y, et al.
bioRxiv
. 2023 May;
PMID: 37215033
Crosstalk between metabolism and stress-responsive signaling is essential to maintaining cellular homeostasis. One way this crosstalk is achieved is through the covalent modification of proteins by endogenous, reactive metabolites that...
7.
Ko Y, Hong M, Lee S, Kumar M, Ibrahim L, Nutsch K, et al.
Proc Natl Acad Sci U S A
. 2023 May;
120(20):e2300763120.
PMID: 37155889
KEAP1 (Kelch-like ECH-associated protein), a cytoplasmic repressor of the oxidative stress responsive transcription factor Nuclear factor erythroid 2-related factor 2 (NRF2), senses the presence of electrophilic agents by modification of...
8.
Jo J, Kim J, Ibrahim L, Kumar M, Iaconelli J, Tran C, et al.
Bioorg Med Chem Lett
. 2023 Apr;
89:129306.
PMID: 37116763
Activating NRF2-driven transcription with non-electrophilic small molecules represents an attractive strategy to therapeutically target disease states associated with oxidative stress and inflammation. In this study, we describe a campaign to...
9.
Shalhout S, Yang P, Grzelak E, Nutsch K, Shao S, Zambaldo C, et al.
Nat Chem Biol
. 2021 Mar;
17(7):767-775.
PMID: 33723431
The transcriptional coactivator Yes-associated protein 1 (YAP) orchestrates a proproliferative transcriptional program that controls the fate of somatic stem cells and the regenerative responses of certain tissues. As such, agents...
10.
Jo J, Ibrahim L, Iaconelli J, Kwak J, Kumar M, Jung Y, et al.
Bioorg Chem
. 2021 Jan;
108:104614.
PMID: 33508678
The transcription factor NRF2 controls resistance to oxidative insult and is thus a key therapeutic target for treating a number of disease states associated with oxidative stress and aging. We...