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Lanying Q Hatcher

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Articles 9
Citations 180
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Recent Articles
1.
Hatcher L, Hong L, Bush W, Carducci T, Simon J
J Phys Chem B . 2008 Jun; 112(27):8160-4. PMID: 18558757
The amyloid beta (A beta) peptide of Alzheimer's disease binds copper(II), and the peptide-bound metal may be a source of reactive oxygen species and neurotoxicity. To circumvent peptide aggregation and...
2.
Hatcher L, Simon J
Photochem Photobiol . 2008 Apr; 84(3):608-12. PMID: 18422878
The detailed structure of melanin remains elusive due to the complexity and insolubility of the pigment. Herein we describe a novel oxidation of 5,6-dihydroxyindole (DHI) as a means to characterize...
3.
Hong L, Bush W, Hatcher L, Simon J
J Phys Chem B . 2007 Nov; 112(2):604-11. PMID: 18027923
An accurate data analysis method for determining stoichiometry and thermodynamic parameters from isothermal titration calorimetry data for the binding of macromolecules to metal cations that are solubilized through an association...
4.
Lee D, Hatcher L, Vance M, Sarangi R, Milligan A, Narducci Sarjeant A, et al.
Inorg Chem . 2007 Jun; 46(15):6056-68. PMID: 17580938
In order to contribute to an understanding of the effects of thioether sulfur ligation in copper-O(2) reactivity, the tetradentate ligands L(N3S) (2-ethylthio-N,N-bis(pyridin-2-yl)methylethanamine) and L(N3S')(2-ethylthio-N,N-bis(pyridin-2-yl)ethylethanamine) have been synthesized. Corresponding copper(I) complexes,...
5.
Hatcher L, Lee D, Vance M, Milligan A, Sarangi R, Hodgson K, et al.
Inorg Chem . 2006 Dec; 45(25):10055-7. PMID: 17140210
Employing a tetradentate N3S(thioether) ligand, LN3S, dioxygen reactivity of a copper(I) complex, [(LN3S)CuI]+ (1) was examined. In CH2Cl2, acetone (at -80 degrees C), or 2-methyltetrahydrofuran (at -128 degrees C), 1...
6.
Hatcher L, Vance M, Narducci Sarjeant A, Solomon E, Karlin K
Inorg Chem . 2006 Mar; 45(7):3004-13. PMID: 16562956
The variation of ligand para substituents on pyridyl donor groups of tridentate amine copper(I) complexes was carried out in order to probe electronic effects on the equilibrium between mu-eta2:eta2-(side-on)-peroxo [Cu(II)2(O2(2-))]2+...
7.
Hatcher L, Karlin K
J Biol Inorg Chem . 2004 Aug; 9(6):669-83. PMID: 15311336
The considerable recent advances in copper-dioxygen coordination chemistry demonstrate the existence of a variety of dioxygen-derived Cu(n)-O(2) complexes, forming a basis for discussion of alternate oxidant types in copper chemistry...
8.
Liang H, Henson M, Hatcher L, Vance M, Zhang C, Lahti D, et al.
Inorg Chem . 2004 Jul; 43(14):4115-7. PMID: 15236520
A new tridentate ligand, PYAN, is employed to investigate solvent influences for dioxygen reactivity with [Cu(PYAN)(MeCN)]B(C(6)F(5))(4) (1). Stopped-flow kinetic studies confirm that the adducts [[u(II)(PYAN)]2)(O(2))][B(C(6)F(5))(4)](2) (2(Peroxo)) and [[u(III)(PYAN)]2)(O)(2)][B(C(6)F(5))(4)](2) (2(Oxo)) are...
9.
Shearer J, Zhang C, Hatcher L, Karlin K
J Am Chem Soc . 2003 Oct; 125(42):12670-1. PMID: 14558790
Copper-dioxygen adducts are important biological oxidants. To gain a better understanding of the underlying chemistries of such species, we report on a series of Cu2II-O2 complexes, [{CuII(MePY2)R'}2(O2)](B(C6F5)4)2 (1R') (where (MePY2)R'...