Lane Bushman
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Explore the profile of Lane Bushman including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Yager J, Coyle R, Coleman S, Ellison L, Zheng J, Bushman L, et al.
J Int Assoc Provid AIDS Care
. 2019 Nov;
18:2325958219888457.
PMID: 31750768
Background: Tenofovir diphosphate (TFV-DP) in dried blood spots (DBS) is a strong predictor of viral suppression in persons living with HIV (PLWH). Its association with antiretroviral therapy (ART) resistance remains...
12.
Landovitz R, Beymer M, Kofron R, Amico K, Psaros C, Bushman L, et al.
J Acquir Immune Defic Syndr
. 2017 Sep;
76(5):501-511.
PMID: 28902074
Background: Tenofovir disoproxil fumarate/emtricitabine preexposure prophylaxis (PrEP) is effective against HIV acquisition when taken as prescribed. Strategies that identify and intervene with those challenged by adherence to daily medication are...
13.
Fonsart J, Saragosti S, Taouk M, Peytavin G, Bushman L, Charreau I, et al.
J Antimicrob Chemother
. 2017 Jan;
72(2):478-485.
PMID: 28073964
Objectives: In the ANRS IPERGAY pre-exposure prophylaxis (PrEP) trial, a single dose of tenofovir disoproxil fumarate and emtricitabine was taken orally 2-24 h before sexual intercourse. A sub-study was conducted...
14.
Fuchs E, Kiser J, Hendrix C, Sulkowski M, Radebaugh C, Bushman L, et al.
J Antimicrob Chemother
. 2016 Feb;
71(6):1597-600.
PMID: 26869690
Objectives: The objective of this study was to evaluate the effects of abacavir on intracellular ribavirin triphosphate and plasma ribavirin trough concentrations. Methods: Hepatitis C virus-infected subjects who had been...
15.
Grant R, Anderson P, McMahan V, Liu A, Amico K, Mehrotra M, et al.
Lancet Infect Dis
. 2014 Jul;
14(9):820-9.
PMID: 25065857
Background: The effect of HIV pre-exposure prophylaxis (PrEP) depends on uptake, adherence, and sexual practices. We aimed to assess these factors in a cohort of HIV-negative people at risk of...
16.
Zheng J, Guida L, Rower C, Castillo-Mancilla J, Meditz A, Klein B, et al.
J Pharm Biomed Anal
. 2013 Sep;
88:144-51.
PMID: 24055850
A reversed-phase high performance liquid chromatographic (LC), tandem mass spectrometry (MS/MS) assay for the determination of tenofovir (TFV) and emtricitabine (FTC) in dried blood spots (DBS) from human whole blood...
17.
Kiser J, Bumpass J, Meditz A, Anderson P, Bushman L, Ray M, et al.
Antimicrob Agents Chemother
. 2010 Oct;
54(12):4999-5003.
PMID: 20921313
Raltegravir's divalent metal ion chelating motif may predispose the drug to interactions with divalent cations. We determined whether a divalent cation-containing antacid interacted with raltegravir. Twelve HIV-1-seronegative subjects were enrolled...
18.
Delahunty T, Bushman L, Robbins B, Fletcher C
J Chromatogr B Analyt Technol Biomed Life Sci
. 2009 Jun;
877(20-21):1907-14.
PMID: 19493710
An LC/MS/MS assay we published for tenofovir (TFV) plasma levels is a useful tool for monitoring the pharmacotherapy of HIV-positive individuals [T. Delahunty, L. Bushman, C.V. Fletcher, J. Chromatogr. B...
19.
King T, Bushman L, Kiser J, Anderson P, Ray M, Delahunty T, et al.
J Chromatogr B Analyt Technol Biomed Life Sci
. 2006 Jul;
843(2):147-56.
PMID: 16828350
To facilitate the evaluation of drug safety, virologic activity, and pharmacokinetics, an anion exchange isolation of tenofovir-diphosphate (TFV-DP) from human peripheral blood mononuclear cells (hPBMCs), coupled with dephosphorylation, desaltation, and...
20.
King T, Bushman L, Anderson P, Delahunty T, Ray M, Fletcher C
J Chromatogr B Analyt Technol Biomed Life Sci
. 2006 Jan;
831(1-2):248-57.
PMID: 16412710
To facilitate the assessment of drug safety and determination of phamacokinetics, an anion exchange isolation of zidovudine triphosphate (ZDV-TP) from human peripheral blood mononuclear cells (hPBMC), coupled with dephosphorylation, desaltation,...