Lale A Ertuglu
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Explore the profile of Lale A Ertuglu including associated specialties, affiliations and a list of published articles.
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33
Citations
376
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Recent Articles
1.
Masenga S, Wandira N, Cattivelli-Murdoch G, Saleem M, Beasley H, Hinton Jr A, et al.
Nat Rev Cardiol
. 2025 Feb;
PMID: 39984695
Salt sensitivity of blood pressure (SSBP) is an independent risk factor for cardiovascular disease in individuals with or without hypertension. However, the mechanisms and management of SSBP remain unclear, mainly...
2.
Dilaver R, Demirci M, Crescenzi R, Pridmore M, Ertuglu L, Guide A, et al.
medRxiv
. 2025 Feb;
PMID: 39974089
Background And Aims: Sarcopenia, defined as a loss in muscle mass and strength, is common in patients with advanced chronic kidney disease (CKD), leading to poor outcomes. Intermuscular adipose tissue...
3.
Saleem M, Aden L, Mutchler A, Basu C, Ertuglu L, Sheng Q, et al.
Circ Res
. 2024 Sep;
135(9):890-909.
PMID: 39263750
Background: Salt sensitivity of blood pressure (SSBP), characterized by acute changes in blood pressure with changes in dietary sodium intake, is an independent risk factor for cardiovascular disease and mortality...
4.
Ertuglu L, Sahinoz M, Alsouqi A, Deger S, Guide A, Pike M, et al.
Physiol Rep
. 2024 Jul;
12(13):e16127.
PMID: 38960895
Background And Aims: High tissue sodium accumulation and intermuscular adipose tissue (IMAT) are associated with aging, type 2 diabetes, and chronic kidney disease. In this study, we aim to investigate...
5.
Albritton C, Demirci M, Neikirk K, Ertuglu L, Ishimwe J, Mutchler A, et al.
bioRxiv
. 2024 Jun;
PMID: 38915603
Background: Salt sensitivity of blood pressure (SSBP) is an independent risk factor for cardiovascular morbidity and mortality, yet the etiology is poorly understood. We previously found that serum/glucocorticoid-regulated kinase 1...
6.
Ertuglu L, Deger S, Alsouqi A, Hung A, Gamboa J, Mambungu C, et al.
J Cachexia Sarcopenia Muscle
. 2024 Jan;
15(1):401-411.
PMID: 38178557
Background: Chronic inflammation and insulin resistance are highly prevalent in patients on maintenance haemodialysis (MHD) and are strongly associated with protein energy wasting. We conducted a pilot, randomized, placebo-controlled trial...
7.
Ertuglu L, Pitzer Mutchler A, Jamison S, Laffer C, Elijovich F, Saleem M, et al.
Hypertension
. 2023 Sep;
81(3):516-529.
PMID: 37675576
Background: The mechanisms by which salt increases blood pressure in people with salt sensitivity remain unclear. Our previous studies found that high sodium enters antigen-presenting cells (APCs) via the epithelial...
8.
Ertuglu L, Pitzer Mutchler A, Elijovich F, Laffer C, Sheng Q, Wanjalla C, et al.
Front Physiol
. 2023 Aug;
14:1208270.
PMID: 37534363
Salt sensitivity of blood pressure is a phenomenon in which blood pressure changes according to dietary sodium intake. Our previous studies found that high salt activates antigen presenting cells, resulting...
9.
High tissue-sodium associates with systemic inflammation and insulin resistance in obese individuals
Ertuglu L, Sahinoz M, Alsouqi A, Deger S, Guide A, Stewart T, et al.
Nutr Metab Cardiovasc Dis
. 2023 May;
33(7):1398-1406.
PMID: 37156670
Background And Aims: High sodium intake is associated with obesity and insulin resistance, and high extracellular sodium content may induce systemic inflammation, leading to cardiovascular disease. In this study, we...
10.
Ahmad T, Ertuglu L, Masenga S, Kleyman T, Kirabo A
Front Cardiovasc Med
. 2023 May;
10:1130148.
PMID: 37123470
A major regulator of blood pressure and volume homeostasis in the kidney is the epithelial sodium channel (ENaC). ENaC is composed of alpha(α)/beta(β)/gamma(γ) or delta(δ)/beta(β)/gamma(γ) subunits. The δ subunit is...